Effect of epidermal growth factor-like peptides on the metabolism of in vitro-matured mouse oocytes and cumulus cells
Oocyte in vitro maturation (IVM) is an assisted reproductive technology that involves the
maturation of cumulus-oocyte complexes (COCs) that are then capable of normal …
maturation of cumulus-oocyte complexes (COCs) that are then capable of normal …
Mode of oocyte maturation affects EGF-like peptide function and oocyte competence
The function and impact of epidermal growth factor (EGF)-like peptide signalling during
ovulation and in vivo oocyte maturation (IVV) has been recently characterized, however, little …
ovulation and in vivo oocyte maturation (IVV) has been recently characterized, however, little …
Role for cumulus cell-produced EGF-like ligands during primate oocyte maturation in vitro
JK Nyholt de Prada, YS Lee… - American Journal …, 2009 - journals.physiology.org
The developmental competence of in vitro-matured (IVM) rhesus macaque cumulus oocyte
complexes (COCs) is deficient compared with in vivo-matured (IVM) oocytes. To improve …
complexes (COCs) is deficient compared with in vivo-matured (IVM) oocytes. To improve …
Pre‐maturation with cAMP modulators in conjunction with EGF‐like peptides during in vitro maturation enhances mouse oocyte developmental competence
D Richani, X Wang, HT Zeng, J Smitz… - Molecular …, 2014 - Wiley Online Library
Recent studies have independently shown that cyclic adenosine 3′ 5′‐monophosphate
(cAMP) modulation prior to in vitro maturation (IVM) and epidermal growth factor (EGF)‐like …
(cAMP) modulation prior to in vitro maturation (IVM) and epidermal growth factor (EGF)‐like …
Epiregulin can effectively mature isolated cumulus–oocyte complexes, but fails as a substitute for the hCG/epidermal growth factor stimulus on cultured follicles
S Romero, J Smitz - Reproduction, 2009 - rep.bioscientifica.com
Epiregulin mediates LH ovulatory effects in vitro. This study evaluated the use of epiregulin
as an alternative to hCG/epidermal growth factor (EGF) stimulus upon cultured ovarian …
as an alternative to hCG/epidermal growth factor (EGF) stimulus upon cultured ovarian …
EGF‐like peptides mediate FSH‐induced maturation of cumulus cell‐enclosed mouse oocytes
SM Downs, J Chen - Molecular Reproduction and …, 2008 - Wiley Online Library
This study was carried out to examine the participation of epidermal growth factor (EGF)‐like
peptides in the induction of germinal vesicle breakdown (GVB) in mouse cumulus cell …
peptides in the induction of germinal vesicle breakdown (GVB) in mouse cumulus cell …
Direct positive effect of epidermal growth factor on the cytoplasmic maturation of mouse and human oocytes
K Das, LE Stout, HC Hensleigh, GE Tagatz… - Fertility and sterility, 1991 - Elsevier
Objective Immature mammalian oocytes cultured in vitro undergo inadequate cytoplasmic
maturation and hence have a limited potential for fertilization. Our primary objective was to …
maturation and hence have a limited potential for fertilization. Our primary objective was to …
In vitro maturation of human germinal vesicle-stage oocytes: role of epidermal growth factor-like growth factors in the culture medium
BACKGROUND In vitro maturation (IVM) of oocytes is a promising technique to reduce the
costs and avert the side effects of gonadotrophin stimulation for IVF. The pregnancy rates …
costs and avert the side effects of gonadotrophin stimulation for IVF. The pregnancy rates …
Epidermal growth factor enhances preimplantation developmental competence of maturing mouse oocytes
R De La Fuente, MJ O'Brien, JJ Eppig - Human Reproduction, 1999 - academic.oup.com
The objective of this study was to determine whether epidermal growth factor (EGF)
promotes nuclear and cytoplasmic maturation of mouse oocytes grown in vivo or in vitro. In …
promotes nuclear and cytoplasmic maturation of mouse oocytes grown in vivo or in vitro. In …
Epidermal growth factor in human follicular fluid stimulates mouse oocyte maturation in vitro
K Das, WR Phipps, HC Hensleigh, GE Tagatz - Fertility and sterility, 1992 - Elsevier
Objective To study the effect of human follicular fluid (FF) and the specific contribution of its
epidermal growth factor (EGF) component on the in vitro maturation of cumulus-enclosed …
epidermal growth factor (EGF) component on the in vitro maturation of cumulus-enclosed …