Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer.

KA Fleming, A McMichael, JA Morton… - Journal of Clinical …, 1981 - jcp.bmj.com
With a monoclonal antibody which reacts with all HLA class 1 antigens it was found that
these antigens are not uniformly distributed in all nucleated cells. Rather HLA class 1 …

High frequency of altered HLA class I phenotypes in invasive breast carcinomas

T Cabrera, MA Fernandez, A Sierra, A Garrido… - Human immunology, 1996 - Elsevier
We studied 105 tumor samples obtained from patients diagnosed as having breast
carcinomas for HLA class I and II (DR) antigen expression, using a panel of mAbs defining …

Expression of HLA-A, B, C antigens on primary and metastatic tumor cell populations of human carcinomas

C Cordon-Cardo, Z Fuks, M Drobnjak, C Moreno… - Cancer research, 1991 - AACR
The expression of monomorphic determinants of the histocompatibility leukocyte antigens
(HLA) class I antigens by human malignant tumor cells was studied in tissue specimens of …

Heterogeneity of the expression of class I and II HLA antigens in human breast carcinoma

M Perez, T Cabrera, MA Lopez Nevot… - International Journal …, 1986 - Wiley Online Library
SUMMARY HLA class I and II antigen expression was studied in 19 cases of primary
infiltrating ductal carcinoma of the breast. An indirect immunofluorescence technique was …

Selective changes in expression of HLA class I polymorphic determinants in human solid tumors.

PG Natali, MR Nicotra, A Bigotti… - Proceedings of the …, 1989 - National Acad Sciences
Analysis of surgical biopsies with monoclonal antibodies (mAbs) to framework determinants
of major histocompatibility complex class I antigens has shown that malignant transformation …

Heterogeneity in the expression of HLA and tumor-associated antigens by surgically removed and cultured breast carcinoma cells

PG Natali, P Giacomini, A Bigotti, K Imai, MR Nicotra… - Cancer Research, 1983 - AACR
Surgically removed normal and malignant mammary tissues and human breast carcinoma
cell lines were tested in binding assays with monoclonal antibodies to HLA-A, B, C antigens …

Reduced expression of HLA class I and II antigens in colon cancer

CJ McDougall, SS Ngoi, IS Goldman, T Godwin, J Felix… - Cancer research, 1990 - AACR
The expression of HLA class I and II antigens was studied by immunohistochemistry in (a)
specimens of colon cancer from 25 patients,(b) normal colonic mucosa obtained 5–10 cm …

HLA-A2 presents shared tumor-associated antigens derived from endogenous proteins in ovarian cancer.

GE Peoples, PS Goedegebuure… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
Tumor-associated lymphocytes (TAL) from the malignant ascites and tumor-infiltrating
lymphocytes (TIL) from the solid tumor were isolated from six consecutive untreated ovarian …

Expression of the non-classical HLA-G antigen in tumor cell lines is extremely restricted.

K Polakova, G Russ - Neoplasma, 2000 - europepmc.org
It has been proposed that tumor cells frequently associated with partial or total loss of HLA
class Ia expression may abnormally express HLA-G class Ib antigen. Such peculiar HLA …

A mutated HLA-A2 molecule recognized by autologous cytotoxic T lymphocytes on a human renal cell carcinoma.

D Brändle, F Brasseur, P Weynants, T Boon… - The Journal of …, 1996 - rupress.org
Many human tumor cells have been shown to express antigens that are recognized by
autologous cytotoxic T lymphocytes (CTL) and the molecular nature of a number of …