Comprehensive genomic characterization of head and neck squamous cell carcinomas

Cancer Genome Atlas Network Genome sequencing … - Nature, 2015 - nature.com
Abstract The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas
(HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here we …

[HTML][HTML] Comprehensive genomic characterization of head and neck squamous cell carcinomas

Cancer Genome Atlas Network - Nature, 2015 - ncbi.nlm.nih.gov
Abstract The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas
(HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here we …

The mutational landscape of head and neck squamous cell carcinoma

N Stransky, AM Egloff, AD Tward, AD Kostic… - science, 2011 - science.org
Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently
lethal malignancy. To uncover its mutational spectrum, we analyzed whole-exome …

Comprehensive genomic characterization of squamous cell lung cancers

Memorial Sloan-Kettering Cancer Center (TCGA pilot … - Nature, 2012 - nature.com
Lung squamous cell carcinoma is a common type of lung cancer, causing approximately
400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers …

Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss

AM Gross, RK Orosco, JP Shen, AM Egloff, H Carter… - Nature …, 2014 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is characterized by aggressive behavior
with a propensity for metastasis and recurrence. Here we report a comprehensive analysis …

Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma

SV Puram, M Mints, A Pal, Z Qi, A Reeb, K Gelev… - Nature …, 2023 - nature.com
Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …

Comprehensive genomic characterization of squamous cell carcinoma of the head and neck in the Cancer Genome Atlas.

DN Hayes, J Grandis, AK El-Naggar - Cancer Research, 2013 - AACR
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading
causes of cancer death in the United States and Worldwide. Most cancers are tobacco …

Abstract IA09: Comprehensive genomic characterization of head and neck squamous cell carcinomas

JR Grandis - Clinical Cancer Research, 2017 - AACR
Large and comprehensive genomic analyses of head and neck squamous cell carcinomas
(HNSCC) are greatly increasing our understanding of the heterogeneity of this disease and …

Unexpected heterogeneity in oropharyngeal squamous cell tumors

DJ Peace, E Izumchenko, D Sidransky - Nature genetics, 2023 - nature.com
A study uses single-cell RNA sequencing to profile human papillomavirus (HPV)-positive
and-negative oropharyngeal squamous cell carcinoma, revealing considerable diversity …

Head and Neck Cancer: TCGA Genome Studies Confirm Heterogeneity—Reveal Potential Therapeutic Targets and Molecular Subtypes

RS Tuma - 2013 - journals.lww.com
WASHINGTON—Genome-wide studies of head and neck squamous cell cancer (HNSCC)
show that tumors driven by human papillomavirus (HPV) are molecularly distinct from other …