Recent advances in clustering methods for protein interaction networks

J Wang, M Li, Y Deng, Y Pan - BMC genomics, 2010 - Springer
The increasing availability of large-scale protein-protein interaction data has made it
possible to understand the basic components and organization of cell machinery from the …

Clustering algorithms for detecting functional modules in protein interaction networks

L Gao, PG Sun, J Song - Journal of Bioinformatics and …, 2009 - World Scientific
Protein–Protein Interaction (PPI) networks are believed to be important sources of
information related to biological processes and complex metabolic functions of the cell …

An ensemble framework for clustering protein–protein interaction networks

S Asur, D Ucar, S Parthasarathy - Bioinformatics, 2007 - academic.oup.com
Abstract Motivation: Protein–Protein Interaction (PPI) networks are believed to be important
sources of information related to biological processes and complex metabolic functions of …

Evaluation of clustering algorithms for protein-protein interaction networks

S Brohee, J Van Helden - BMC bioinformatics, 2006 - Springer
Background Protein interactions are crucial components of all cellular processes. Recently,
high-throughput methods have been developed to obtain a global description of the …

A fast hierarchical clustering algorithm for functional modules discovery in protein interaction networks

J Wang, M Li, J Chen, Y Pan - IEEE/ACM Transactions on …, 2010 - ieeexplore.ieee.org
As advances in the technologies of predicting protein interactions, huge data sets portrayed
as networks have been available. Identification of functional modules from such networks is …

Detection of protein complexes in protein interaction networks using n-clubs

S Pasupuleti - … on Evolutionary Computation, Machine Learning and …, 2008 - Springer
Protein complexes, identified as functional modules in protein interaction networks, are
cellular entities that perform certain biological functions. Revealing these modular structures …

A novel functional module detection algorithm for protein-protein interaction networks

W Hwang, YR Cho, A Zhang… - Algorithms for Molecular …, 2006 - Springer
Background The sparse connectivity of protein-protein interaction data sets makes
identification of functional modules challenging. The purpose of this study is to critically …

An automated method for finding molecular complexes in large protein interaction networks

GD Bader, CWV Hogue - BMC bioinformatics, 2003 - Springer
Background Recent advances in proteomics technologies such as two-hybrid, phage
display and mass spectrometry have enabled us to create a detailed map of biomolecular …

Multifunctional proteins revealed by overlapping clustering in protein interaction network

E Becker, B Robisson, CE Chapple, A Guénoche… - …, 2012 - academic.oup.com
Motivation: Multifunctional proteins perform several functions. They are expected to interact
specifically with distinct sets of partners, simultaneously or not, depending on the function …

Functional clustering of yeast proteins from the protein-protein interaction network

TZ Sen, A Kloczkowski, RL Jernigan - BMC bioinformatics, 2006 - Springer
Background The abundant data available for protein interaction networks have not yet been
fully understood. New types of analyses are needed to reveal organizational principles of …