Development of white matter hyperintensity is preceded by reduced cerebrovascular reactivity
Objective White matter hyperintensities (WMH) observed on neuroimaging of elderly
individuals are associated with cognitive decline and disability. However, the pathogenesis …
individuals are associated with cognitive decline and disability. However, the pathogenesis …
Cerebral perfusion and cerebrovascular reactivity are reduced in white matter hyperintensities
JR Marstrand, E Garde, E Rostrup, P Ring… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—There is growing evidence that white matter hyperintensities
(WMH) should not be considered as benign age-dependent changes on MR images but …
(WMH) should not be considered as benign age-dependent changes on MR images but …
Progression of white matter hyperintensities preceded by heterogeneous decline of microstructural integrity
EMC Van Leijsen, MI Bergkamp, IWM Van Uden… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—White matter hyperintensities (WMH) are frequently seen on
neuroimaging of elderly and are associated with cognitive decline and the development of …
neuroimaging of elderly and are associated with cognitive decline and the development of …
[HTML][HTML] Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures
N Promjunyakul, D Lahna, JA Kaye, HH Dodge… - NeuroImage: Clinical, 2015 - Elsevier
Abstract Objective White matter hyperintensities (WMHs) are common with age, grow over
time, and are associated with cognitive and motor impairments. Mechanisms underlying …
time, and are associated with cognitive and motor impairments. Mechanisms underlying …
[HTML][HTML] White matter hyperintensities and normal-appearing white matter integrity in the aging brain
SM Maniega, MCV Hernández, JD Clayden… - Neurobiology of …, 2015 - Elsevier
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in
brain magnetic resonance imaging of older individuals and contribute to cognitive and …
brain magnetic resonance imaging of older individuals and contribute to cognitive and …
White matter hyperintensities, cognitive impairment and dementia: an update
ND Prins, P Scheltens - Nature Reviews Neurology, 2015 - nature.com
White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small
vessel disease, and can easily be detected on MRI. Over the past three decades, research …
vessel disease, and can easily be detected on MRI. Over the past three decades, research …
The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment
G Tosto, ME Zimmerman, JL Hamilton… - Alzheimer's & …, 2015 - Elsevier
Introduction It is unclear whether white matter hyperintensities (WMHs), magnetic resonance
imaging markers of small-vessel cerebrovascular disease, promote neurodegeneration and …
imaging markers of small-vessel cerebrovascular disease, promote neurodegeneration and …
The impact of magnetic resonance imaging-detected white matter hyperintensities on longitudinal changes in regional cerebral blood flow
MA Kraut, LL Beason-Held… - Journal of Cerebral …, 2008 - journals.sagepub.com
White matter hyperintensities are frequently detected on cranial magnetic resonance
imaging (MRI) scans of older adults. Given the presumed ischemic contribution to the …
imaging (MRI) scans of older adults. Given the presumed ischemic contribution to the …
Cerebral small vessel disease in aging and A lzheimer's disease: a comparative study using MRI and SPECT
I Makedonov, SE Black… - European journal of …, 2013 - Wiley Online Library
Background White matter hyperintensities (WMH) are associated with aging and are
prevalent in various brain pathologies. The purpose of the current study was to characterize …
prevalent in various brain pathologies. The purpose of the current study was to characterize …
Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function
White matter hyperintensities (WMH) of presumed vascular origin, as seen on T2-weighted
fluid attenuated inversion recovery magnetic resonance imaging, are known to increase with …
fluid attenuated inversion recovery magnetic resonance imaging, are known to increase with …