RNA-seq data science: From raw data to effective interpretation

D Deshpande, K Chhugani, Y Chang… - Frontiers in …, 2023 - frontiersin.org
RNA sequencing (RNA-seq) has become an exemplary technology in modern biology and
clinical science. Its immense popularity is due in large part to the continuous efforts of the …

Advanced applications of RNA sequencing and challenges

Y Han, S Gao, K Muegge, W Zhang… - … and biology insights, 2015 - journals.sagepub.com
Next-generation sequencing technologies have revolutionarily advanced sequence-based
research with the advantages of high-throughput, high-sensitivity, and high-speed. RNA-seq …

Bioinformatics for RNA-seq data analysis

S Zhao, B Zhang, Y Zhang, W Gordon… - Bioinformatics …, 2016 - books.google.com
While RNA sequencing (RNA-seq) has become increasingly popular for transcriptome
profiling, the analysis of the massive amount of data generated by large-scale RNA-seq still …

RNA-Seq analysis: methods, applications and challenges

F Geraci, I Saha, M Bianchini - Frontiers in Genetics, 2020 - frontiersin.org
RNA-seq has revolutionized the research community approach to studying gene expression.
In fact, this technology has opened up the possibility of quantifying the expression level of all …

A survey of best practices for RNA-seq data analysis

A Conesa, P Madrigal, S Tarazona, D Gomez-Cabrero… - Genome biology, 2016 - Springer
Abstract RNA-sequencing (RNA-seq) has a wide variety of applications, but no single
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …

RNA sequencing data: hitchhiker's guide to expression analysis

K Van den Berge, KM Hembach… - Annual Review of …, 2019 - annualreviews.org
Gene expression is the fundamental level at which the results of various genetic and
regulatory programs are observable. The measurement of transcriptome-wide gene …

Revealing the history and mystery of RNA-Seq

A Gondane, HM Itkonen - Current Issues in Molecular Biology, 2023 - mdpi.com
Advances in RNA-sequencing technologies have led to the development of intriguing
experimental setups, a massive accumulation of data, and high demand for tools to analyze …

Modeling and analysis of RNA‐seq data: a review from a statistical perspective

WV Li, JJ Li - Quantitative Biology, 2018 - Wiley Online Library
Background Since the invention of next‐generation RNA sequencing (RNA‐seq)
technologies, they have become a powerful tool to study the presence and quantity of RNA …

Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

RNA‐seq: Basic bioinformatics analysis

F Ji, RI Sadreyev - Current protocols in molecular biology, 2018 - Wiley Online Library
Quantitative analysis of gene expression is crucial for understanding the molecular
mechanisms underlying genome regulation. RNA‐seq is a powerful platform for …