Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …

Simple Summary Research on leukemia has often led to novel approaches in clinical
practice. Cytogenetical and molecular markers have been introduced in treatment protocols …

Recent studies have revealed that non-coding regions comprise the vast majority of the
human genome and long non-coding RNAs (lncRNAs) are a diverse class of non-coding …

Cancer is a physiological condition that has both the endogenous and exogenous
influences on its progression. It originates from unusual cell growth, where the cells undergo …

Leukemia is a common malignant cancer of the hematopoietic system, whose pathogenesis
has not been fully elucidated. Long noncoding RNAs (lncRNAs) are transcripts longer than …

Acute leukemia (AL) is the main type of cancer in children worldwide. Mortality by this
disease is high in developing countries and its etiology remains unanswered. Evidences …

Acute myeloid leukemia (AML) is a common hematological disorder with heterogeneous
nature that resulted from blocked myeloid differentiation and an enhanced number of …

Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides in
length. LncRNAs are as diverse as mRNAs and they normally share the same biosynthetic …

Acute myeloid leukemia (AML) represents 80% of adult leukemias and 15–20% of childhood
leukemias. AML are characterized by the presence of 20% blasts or more in the bone …

With the advent of novel high throughput techniques, an extensive number of non-coding
RNAs have been recognized to be involved in the pathogenesis of different types of …