TiO2 nanoparticles induce DNA double strand breaks and cell cycle arrest in human alveolar cells

K Kansara, P Patel, D Shah, RK Shukla… - Environmental and …, 2015 - Wiley Online Library
TiO2 nanoparticles (NPs) have the second highest global annual production (∼ 3000 tons)
among the metal‐containing NPs. These NPs are used as photocatalysts for bacterial …

Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

L Armand, A Tarantini, D Beal, M Biola-Clier… - …, 2016 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2-NPs) are one of the most produced NPs in the
world. Their toxicity has been studied for a decade using acute exposure scenarios, ie high …

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

B Trouiller, R Reliene, A Westbrook, P Solaimani… - Cancer research, 2009 - AACR
Titanium dioxide (TiO2) nanoparticles are manufactured worldwide in large quantities for
use in a wide range of applications including pigment and cosmetic manufacturing. Although …

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

ML Jugan, S Barillet, A Simon-Deckers… - …, 2012 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2-NPs) are produced in large quantities, raising
concerns about their impact for human health. The aim of this study was to deeply …

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

M Biola-Clier, D Béal, S Caillat, S Libert, L Armand… - …, 2017 - academic.oup.com
For some decades production of titanium dioxide nanoparticle (TiO2-NP) has been
increasing at a considerable rate; concerns as to the toxicity of these particles upon …

[HTML][HTML] Toxicological Consequences of Titanium Dioxide Nanoparticles (TiO2NPs) and Their Jeopardy to Human Population

S Shabbir, MFA Kulyar, ZA Bhutta, P Boruah, M Asif - BioNanoScience, 2021 - Springer
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are the most produced nanomaterial for
food additives, pigments, photocatalysis, and personal care products. These nanomaterials …

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

RK Shukla, V Sharma, AK Pandey, S Singh, S Sultana… - Toxicology in vitro, 2011 - Elsevier
Titanium dioxide nanoparticles (TiO2 NPs) are among the top five NPs used in consumer
products, paints and pharmaceutical preparations. Since, exposure to such nanoparticles is …

[HTML][HTML] Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y)

F Brandão, N Fernández-Bertólez, F Rosário… - Nanomaterials, 2020 - mdpi.com
Titanium dioxide nanoparticles (TiO2 NPs) have a wide variety of applications in many
consumer products, including as food additives, increasing the concern about the possible …

[HTML][HTML] Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells

K Bhattacharya, M Davoren, J Boertz… - Particle and fibre …, 2009 - Springer
Abstract Titanium dioxide (TiO 2), also known as titanium (IV) oxide or anatase, is the
naturally occurring oxide of titanium. It is also one of the most commercially used form. To …

[HTML][HTML] Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vivo and In Vitro: A Meta-Analysis

Y Cao, J Chen, Q Bian, J Ning, L Yong, T Ou, Y Song… - Toxics, 2023 - mdpi.com
Background: Recent studies have raised concerns about genotoxic effects associated with
titanium dioxide nanoparticles (TiO2 NPs), which are commonly used. This meta-analysis …