Stimuli-responsive polymers are promising to achieve targeted delivery, improved stability
during circulation, and controlled release of therapeutic and diagnostic agents. Among them …

The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Various pH-sensitive polymers have been developed for biomedical applications and
recently attracted much attention for pH targeting nanomedicine. Recent development of pH …

Cancer remains a leading cause of death worldwide with more than 10 million new cases
every year. Tumor-targeted nanomedicines have shown substantial improvements of the …

Polymer–drug conjugates are becoming established as a shining platform for drug delivery.
Incorporation of pH-responsive linker between drug and polymer is expected to realize …

Abstract pH-sensitive smart polymeric nanocarriers have been under development in the
field of biomedicine due to permeabilization the physiological barriers readily to address the …

For decades, researchers have aspired to develop materials for noninvasive treatment and
monitoring of pathological conditions. Various organs, tissues, subcellular compartments …

Over the past decades, nanoparticle-based drug-delivery systems (DDS) have received
extensive attention in cancer therapy owing to their improved pharmacokinetics and …

As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

The conventional chemotherapeutic agents, used for cancer chemotherapy, have major
limitations including non-specificity, ubiquitous biodistribution, low concentration in tumor …