Autism spectrum disorders (ASDs) now affect 1–2% of the children born in the United States.
Hundreds of genetic, metabolic and environmental factors are known to increase the risk of …

Background Autism spectrum disorders (ASDs) are caused by both genetic and
environmental factors. Mitochondria act to connect genes and environment by regulating …

Autism spectrum disorder (ASD) is characterized by deficits in communication and social
interaction, restricted interests, and stereotyped behavior. Environmental factors, such as …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology.
The core syndromes of ASD are deficits in social communication and self-restricted interests …

Background This study was designed to test a new approach to drug treatment of autism
spectrum disorders (ASDs) in the Fragile X (Fmr1) knockout mouse model. Methods We …

Since 2012, studies in mice, rats, and humans have suggested that abnormalities in
purinergic signaling may be a final common pathway for many genetic and environmental …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with a
high prevalence rate. The core symptoms of ASD patients are impaired social …

Background The amygdala controls socioemotional behavior and has consistently been
implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala …

Autism spectrum disorders (ASD) are characterized by altered sociability, compromised
communication and stereotyped/repetitive behaviors, for which no specific treatments are …

Objective No drug is yet approved to treat the core symptoms of autism spectrum disorder
(ASD). Low‐dose suramin was effective in the maternal immune activation and Fragile X …