Structural basis for PECAM-1 homophilic binding

C Paddock, D Zhou, P Lertkiatmongkol… - Blood, The Journal …, 2016 - ashpublications.org
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kDa member of the
immunoglobulin gene superfamily (IgSF) that is present on the surface of circulating …

Atomic level dissection of the platelet endothelial cell adhesion molecule 1 (PECAM-1) homophilic binding interface: implications for endothelial cell barrier function

D Liao, J Sundlov, J Zhu, H Mei, Y Hu… - … and Vascular Biology, 2022 - Am Heart Assoc
Objective: PECAM-1 (platelet endothelial cell adhesion molecule 1) is a 130 kDa member of
the immunoglobulin (Ig) gene superfamily that is expressed on the surfaces of platelets and …

[HTML][HTML] Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the …

J Sun, J Williams, HC Yan, KM Amin… - Journal of Biological …, 1996 - ASBMB
PECAM-1/CD31 is vascular cell adhesion and signaling molecule of the Ig superfamily that
plays a role in neutrophil recruitment at inflammatory sites and may be involved the release …

Fluorescencein SituHybridization Mapping of the Mouse Platelet Endothelial Cell Adhesion Molecule-1 (PECAM1) to Mouse Chromosome 6, Region F3–G1

Y Xie, WA Muller - Genomics, 1996 - Elsevier
Human platelet/endothelial cell adhesion molecule-1 (PECAM1), an important member of
the immunoglobulin gene superfamily, is widely distributed on cells of the vascular system …

Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificity

J Famiglietti, J Sun, HM DeLisser… - The Journal of cell …, 1997 - rupress.org
Platelet/endothelial cell adhesion molecule (PECAM-1) is a cell adhesion molecule of the
immunoglobulin superfamily that plays a role in a number of vascular processes including …

[HTML][HTML] The role of sialylated glycans in human platelet endothelial cell adhesion molecule 1 (PECAM-1)-mediated trans homophilic interactions and endothelial cell …

P Lertkiatmongkol, C Paddock, DK Newman… - Journal of Biological …, 2016 - ASBMB
Abstract Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) is a major component of
the endothelial cell intercellular junction. Previous studies have shown that PECAM-1 …

Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties

HM DeLisser, J Chilkotowsky, HC Yan… - The Journal of cell …, 1994 - rupress.org
Platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the
immunoglobulin superfamily present on platelets, endothelial cells, and leukocytes that may …

[HTML][HTML] Structural basis for human PECAM-1-mediated trans-homophilic cell adhesion

M Hu, H Zhang, Q Liu, Q Hao - Scientific Reports, 2016 - nature.com
Cell adhesion involved in signal transduction, tissue integrity and pathogen infection is
mainly mediated by cell adhesion molecules (CAM). One CAM member, platelet–endothelial …

[HTML][HTML] Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1)

H Mei, JM Campbell, CM Paddock… - Journal of Biological …, 2014 - ASBMB
PECAM-1 is a 130-kDa member of the immunoglobulin (Ig) superfamily that is expressed on
the surface of platelets and leukocytes, and at the intracellular junctions of confluent …

Platelet endothelial cell adhesion molecule 1 (PECAM-1) and its interactions with glycosaminoglycans: 1. Molecular modeling studies

NS Gandhi, DR Coombe, RL Mancera - Biochemistry, 2008 - ACS Publications
Platelet endothelial cell adhesion molecule 1 (PECAM-1) has many functions, including its
roles in leukocyte extravasation as part of the inflammatory response and in the …