Pretreatment cytogenetics is a known predictor of outcome in hematologic malignancies.
However, its usefulness in adult acute lymphoblastic leukemia (ALL) is generally limited to …

We examined the prognostic impact of cytogenetics on the outcome of 200 acute
lymphoblastic leukemia (ALL) patients 15 to 65 years of age enrolled in Southwest Oncology …

Abstract The Cancer and Leukemia Group B (CALGB) has been conducting a prospective
cytogenetic companion study (CALGB 8461) to all CALGB treatment protocols for newly …

Chromosomal abnormalities are increasingly used to risk stratify adults with acute
lymphoblastic leukemia. Published data describing the age-specific incidence of …

Cytogenetic classification of 350 adults with acute lymphoblastic leukaemia on MRC UKALL
XA trial showed the following statistically significant associations: t (9; 22)(11%) increased …

With intensified pediatric-like therapy and genetic disease dissection, the field of adult acute
lymphoblastic leukemia (ALL) has evolved recently. In this new context, we aimed to …

To evaluate the importance of pretreatment karyotype in predicting long-term outcome in
acute lymphoblastic leukemia (ALL), we performed a follow-up study of the 329 patients from …

Abstract The Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) 0496 protocol,
through the central handling of bone marrow samples at presentation, allowed us to …

The importance of banded chromosome analyses in predicting long-term outcome in acute
lymphoblastic leukemia (ALL) was evaluated in this follow-up study of 329 patients from the …

In the last decades outcome of adult acute lymphoblastic leukemia (ALL) has improved
considerably. In large multicenter studies remission rates range from 75% to 89%, and long …