Barriers to gene flow between naturally hybridizing taxa reveal the initial stages of
speciation. Reduced hybrid fertility is a common feature of reproductive barriers separating …

Reproductive barriers are often assumed to arise from fixed genetic differences between
species, despite frequent individual variation in the strength of reproductive isolation …

Comparative genetic mapping provides insights into the evolution of the reproductive
barriers that separate closely related species. This approach has been used to document …

House mice offer a powerful system for dissecting the genetic basis of phenotypes that
isolate species in the early stages of speciation. We used a series of reciprocal crosses …

Reproductive isolation between species is often caused by deleterious interactions among
loci in hybrids. Finding the genes involved in these incompatibilities provides insight into the …

Mapping hybrid defects in contact zones between incipient species can identify genomic
regions contributing to reproductive isolation and reveal genetic mechanisms of speciation …

Hybrids between new species are often sterile. To understand the causes of this
reproductive barrier, Schwahn et al. examined testis histology in a large number of hybrids …

Studies of a hybrid zone between two house mouse subspecies (Mus musculus musculus
and M. m. domesticus) along with studies using laboratory crosses reveal a large role for the …

One approach to understanding the process of speciation is to characterize the genetic
architecture of post-zygotic isolation. As gene regulation requires interactions between loci …

Barriers to gene flow can arise at any stage in the reproductive sequence. Most studies of
reproductive isolation focus on premating or postzygotic phenotypes, leaving the importance …