Possible cardiac repair by adult stem cell transplantation is currently hampered by poor cell
viability and delivery efficiency, uncertain differentiating fate in vivo, the needs of ex vivo cell …

We have developed a mixed ester of hyaluronan with butyric and retinoic acid (HBR) that
acted as a novel cardiogenic/vasculogenic agent in human mesenchymal stem cells …

Embryonic stem (ES) cells can differentiate into specialized cells, including cardiac
myocytes, but the efficiency is typically low and the process is incompletely understood …

Aims Pre-treating placenta-derived human mesenchymal stem cells (FMhMSCs) with a
hyaluronan mixed ester of butyric and retinoic acid (HBR) potentiates their reparative …

Hyaluronan (HA) has been shown to play an important role during early heart development
and promote angiogenesis under various physiological and pathological conditions. In …

Aims After injury, the adult zebrafish can regenerate the heart. This requires the activation of
the endocardium and epicardium as well as the proliferation of pre-existing cardiomyocytes …

Hyaluronan (HA) is abundantly expressed in several human tissues and a variety of roles for
HA has been highlighted. Particularly relevant for tissue repair, HA is actively produced …

OBJECTIVES The use of stem cells in cardiac regeneration is still limited due to low cellular
integration and engraftment rates. Consequently, there has been a spurt in research on …

The major problem in stem cell therapy includes viability and engraftment efficacy of stem
cells after transplantation. Indeed, the vast majority of host‐transfused cells do not survive …

The limited cardiomyocyte proliferation is insufficient for repair of the myocardium. Therefore,
activating cardiomyocyte proliferation might be a reasonable option for myocardial …