Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza
K Matsuo, S Hirobe, Y Yokota, Y Ayabe, M Seto… - Journal of controlled …, 2012 - Elsevier
Transcutaneous immunization (TCI) is an attractive alternative vaccination route compared
to the commonly used injection systems. We previously developed a dissolving microneedle …
to the commonly used injection systems. We previously developed a dissolving microneedle …
A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens
K Matsuo, Y Yokota, Y Zhai, YS Quan… - Journal of controlled …, 2012 - Elsevier
Transcutaneous immunization (TCI) is a promising needle-free, easy-to-use, and low-
invasive vaccination method. The hydrogel patch-based TCI system induced immune …
invasive vaccination method. The hydrogel patch-based TCI system induced immune …
Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice
Z Ding, FJ Verbaan, M Bivas-Benita, L Bungener… - Journal of Controlled …, 2009 - Elsevier
Transcutaneous immunization (TCI) is limited by poor permeation of macromolecules across
the skin. Microneedle arrays form transient conduits and enhance the transport of vaccine …
the skin. Microneedle arrays form transient conduits and enhance the transport of vaccine …
Microneedle-based vaccines
MR Prausnitz, JA Mikszta, M Cormier… - Vaccines for Pandemic …, 2009 - Springer
The threat of pandemic influenza and other public health needs motivate the development of
better vaccine delivery systems. To address this need, microneedles have been developed …
better vaccine delivery systems. To address this need, microneedles have been developed …
Enhanced transcutaneous immunization via dissolving microneedle array loaded with liposome encapsulated antigen and adjuvant
L Guo, J Chen, Y Qiu, S Zhang, B Xu, Y Gao - International journal of …, 2013 - Elsevier
Transcutaneous immunization (TCI) with dissolving microneedle arrays (DMAs) is a
promising vaccine administration method. In this work, we developed a TCI device …
promising vaccine administration method. In this work, we developed a TCI device …
Microneedle patches for vaccination in developing countries
J Arya, MR Prausnitz - Journal of Controlled Release, 2016 - Elsevier
Millions of people die of infectious diseases each year, mostly in developing countries,
which could largely be prevented by the use of vaccines. While immunization rates have …
which could largely be prevented by the use of vaccines. While immunization rates have …
[HTML][HTML] Development of novel faster-dissolving microneedle patches for transcutaneous vaccine delivery
A Ono, S Ito, S Sakagami, H Asada, M Saito, YS Quan… - Pharmaceutics, 2017 - mdpi.com
Microneedle (MN) patches are promising for transcutaneous vaccination because they
enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin …
enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin …
[HTML][HTML] Microneedles: quick and easy delivery methods of vaccines
KM Kwon, SM Lim, S Choi, DH Kim… - Clinical and …, 2017 - synapse.koreamed.org
Vaccination is the most efficient method for infectious disease prevention. Parenteral
injections such as intramuscular, intradermal, and subcutaneous injections have several …
injections such as intramuscular, intradermal, and subcutaneous injections have several …
[HTML][HTML] Microneedle patches for vaccine delivery
H Suh, J Shin, YC Kim - Clinical and experimental vaccine …, 2014 - synapse.koreamed.org
In today's medical industry, the range of vaccines that exist for administration in humans
represents an eclectic variety of forms and immunologic mechanisms. Namely, these are the …
represents an eclectic variety of forms and immunologic mechanisms. Namely, these are the …
Microneedle-mediated vaccine delivery: harnessing cutaneous immunobiology to improve efficacy
S Al-Zahrani, M Zaric, C McCrudden… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Breaching the skin's stratum corneum barrier raises the possibility of the
administration of vaccines, gene vectors, antibodies and even nanoparticles, all of which …
administration of vaccines, gene vectors, antibodies and even nanoparticles, all of which …