Quantification of ZnO nanoparticle uptake, distribution, and dissolution within individual human macrophages

SA James, BN Feltis, MD de Jonge, M Sridhar… - ACS …, 2013 - ACS Publications
The usefulness of zinc oxide (ZnO) nanoparticles has led to their wide distribution in
consumer products, despite only a limited understanding of how this nanomaterial behaves …

Relating cytotoxicity, zinc ions, and reactive oxygen in ZnO nanoparticle–exposed human immune cells

C Shen, SA James, MD de Jonge… - Toxicological …, 2013 - academic.oup.com
Although zinc oxide (ZnO) nanoparticles (NPs) have been widely formulated in sunscreens,
the relationship between reactive oxygen species (ROS) generation induced by these …

Reducing ZnO nanoparticle cytotoxicity by surface modification

M Luo, C Shen, BN Feltis, LL Martin, AE Hughes… - Nanoscale, 2014 - pubs.rsc.org
Nanoparticulate zinc oxide (ZnO) is one of the most widely used engineered nanomaterials
and its toxicology has gained considerable recent attention. A key aspect for controlling …

[HTML][HTML] The influences of cell type and ZnO nanoparticle size on immune cell cytotoxicity and cytokine induction

C Hanley, A Thurber, C Hanna, A Punnoose… - Nanoscale research …, 2009 - Springer
Nanotechnology represents a new and enabling platform that promises to provide a range of
innovative technologies for biological applications. ZnO nanoparticles of controlled size …

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status

M Prach, V Stone, L Proudfoot - Toxicology and applied pharmacology, 2013 - Elsevier
Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility,
factors which at sublethal concentrations may influence the activation of the human …

Size-dependent effect of zinc oxide on toxicity and inflammatory potential of human monocytes

D Sahu, GM Kannan… - Journal of toxicology and …, 2014 - Taylor & Francis
With the rapid development of nanomedicines, it is important to understand their potential
immunotoxicity. Zinc oxide (ZnO) nanoparticles have several applications in the …

Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview

SR Saptarshi, A Duschl, AL Lopata - Nanomedicine, 2015 - Taylor & Francis
Zinc oxide nanoparticles (ZnO NPs) have useful physicochemical advantages, and are used
extensively. This has raised concerns regarding their potential toxicity. ZnO NP attributes …

Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles

BC Heng, X Zhao, EC Tan, N Khamis, A Assodani… - Archives of …, 2011 - Springer
Zinc oxide (ZnO) nanoparticles have wide-ranging applications in a diverse array of
industrial and consumer products, from ceramic manufacture and paint formulation to …

[HTML][HTML] Effects of serum on cytotoxicity of nano-and micro-sized ZnO particles

IL Hsiao, YJ Huang - Journal of Nanoparticle Research, 2013 - Springer
Although an increasing number of in vitro studies are being published regarding the
cytotoxicity of nanomaterials, the components of the media for toxicity assays have often …

Biological interactions in vitro of zinc oxide nanoparticles of different characteristics

S Aula, S Lakkireddy, AVN Swamy… - Materials Research …, 2014 - iopscience.iop.org
Abstract Zinc oxide nanoparticles (ZnO NPs) have recently received growing attention for
various biomedical applications, including use as therapeutic or carrier for drug delivery …