The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI

SA Kim, IS LaCroix, SA Gerber… - Proceedings of the …, 2019 - National Acad Sciences
Iron is an essential nutrient for plants, but excess iron is toxic due to its catalytic role in the
formation of hydroxyl radicals. Thus, iron uptake is highly regulated and induced only under …

Molecular mechanisms governing Arabidopsis iron uptake

T Brumbarova, P Bauer, R Ivanov - Trends in plant science, 2015 - cell.com
Plants are the principal source of dietary iron (Fe) for most of Earth's population and Fe
deficiency can lead to major health problems. Developing strategies to improve plant Fe …

The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response

EP Colangelo, ML Guerinot - The Plant Cell, 2004 - academic.oup.com
Regulation of iron uptake is critical for plant survival. Although the activities responsible for
reduction and transport of iron at the plant root surface have been described, the genes …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

[HTML][HTML] Arabidopsis bHLH100 and bHLH101 control iron homeostasis via a FIT-independent pathway

AB Sivitz, V Hermand, C Curie, G Vert - 2012 - journals.plos.org
Iron deficiency induces a complex set of responses in plants, including developmental and
physiological changes, to increase iron uptake from soil. In Arabidopsis, many transporters …

All together now: regulation of the iron deficiency response

N Riaz, ML Guerinot - Journal of Experimental Botany, 2021 - academic.oup.com
Iron (Fe) is one of the essential micronutrients required by both plants and animals. In
humans, Fe deficiency causes anemia, the most prevalent nutritional disorder. Most people …

[HTML][HTML] FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis

Y Yuan, H Wu, N Wang, J Li, W Zhao, J Du, D Wang… - Cell research, 2008 - nature.com
Iron is an essential element for plant growth and development. Iron homeostasis in plants is
tightly regulated at both transcriptional and posttranscriptional level. Several bHLH …

Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth‐dependent pathway

M Séguéla, JF Briat, G Vert, C Curie - The Plant Journal, 2008 - Wiley Online Library
Plants display a number of biochemical and developmental responses to low iron
availability in order to increase iron uptake from the soil. The ferric‐chelate reductase FRO2 …

Arabidopsis IRT2 cooperates with the high-affinity iron uptake system to maintain iron homeostasis in root epidermal cells

G Vert, M Barberon, E Zelazny, M Séguéla, JF Briat… - Planta, 2009 - Springer
Iron is an essential nutrient for all organisms but toxic when present in excess.
Consequently, plants carefully regulate their iron uptake, dependent on the FRO2 ferric …

Homing in on iron homeostasis in plants

J Jeong, ML Guerinot - Trends in plant science, 2009 - cell.com
Iron is essential for plants but is not readily accessible and is also potentially toxic. As plants
are a major dietary source of iron worldwide, understanding plant iron homeostasis is pivotal …