Urease as a virulence factor in experimental cryptococcosis
GM Cox, J Mukherjee, GT Cole… - Infection and …, 2000 - Am Soc Microbiol
Urease catalyzes the hydrolysis of urea to ammonia and carbamate and has been found to
be an important pathogenic factor for certain bacteria. Cryptococcus neoformans is a …
be an important pathogenic factor for certain bacteria. Cryptococcus neoformans is a …
Factors required for activation of urease as a virulence determinant in Cryptococcus neoformans
A Singh, RJ Panting, A Varma, T Saijo, KJ Waldron… - MBio, 2013 - Am Soc Microbiol
Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the
brain and causing meningoencephalitis. Although urea is not required for synthesis of …
brain and causing meningoencephalitis. Although urea is not required for synthesis of …
Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung
JJ Osterholzer, R Surana, JE Milam… - The American journal of …, 2009 - Elsevier
Urease, a major virulence factor for Cryptococcus neoformans, promotes lethal meningitis/
encephalitis in mice. The effect of urease within the lung, the primary site of most invasive …
encephalitis in mice. The effect of urease within the lung, the primary site of most invasive …
Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion
MA Olszewski, MC Noverr, GH Chen, GB Toews… - The American journal of …, 2004 - Elsevier
Our objective was to determine the role of the cryptococcal virulence factor urease in
pulmonary-to-central nervous system, dissemination, invasion, and growth. C. neoformans …
pulmonary-to-central nervous system, dissemination, invasion, and growth. C. neoformans …
[HTML][HTML] Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH
MS Fu, C Coelho, CM De Leon-Rodriguez… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with
macrophages is a key event determining the outcome of infection. Urease is a major …
macrophages is a key event determining the outcome of infection. Urease is a major …
Urease inhibition by EDTA in the two varieties of Cryptococcus neoformans
KJ Kwon-Chung, BL Wickes, JL Booth… - Infection and …, 1987 - Am Soc Microbiol
Cryptococcus neoformans var. neoformans (74 isolates) and C. neoformans var. gattii (44
isolates) were used to test urease activity after growth on both yeast extract-glucose-peptone …
isolates) were used to test urease activity after growth on both yeast extract-glucose-peptone …
The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid
JR Perfect, DL Toffaletti, TH Rude - Infection and immunity, 1993 - Am Soc Microbiol
A cryptococcal meningitis model in corticosteroid-treated rabbits was used to assess the
requirement for the phosphoribosylaminoimidazole gene (ADE2) for virulence of …
requirement for the phosphoribosylaminoimidazole gene (ADE2) for virulence of …
[PDF][PDF] Use of a urease test for the screening and identification of cryptococci
HPR Seeliger - Journal of Bacteriology, 1956 - Am Soc Microbiol
RESULTS The results of this study are summarized in table 1. From this table it can be seen
that all strains of Cryptococcus neoformans including the variety Cryptococcus uniguttulatus …
that all strains of Cryptococcus neoformans including the variety Cryptococcus uniguttulatus …
Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
JN Steenbergen, HA Shuman… - Proceedings of the …, 2001 - National Acad Sciences
Cryptococcus neoformans (Cn) is a soil fungus that causes life-threatening meningitis in
immunocompromised patients and is a facultative intracellular pathogen capable of …
immunocompromised patients and is a facultative intracellular pathogen capable of …
Virulence factors of Cryptococcus neoformans
TR Kozel - Trends in microbiology, 1995 - cell.com
Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-
mediated host defenses. Cryptococcus neoformans produces several virulence factors, most …
mediated host defenses. Cryptococcus neoformans produces several virulence factors, most …