[HTML][HTML] Magnetic resonance-based response assessment and dose adaptation in human papilloma virus positive tumors of the oropharynx treated with radiotherapy …
Background Current standard radiotherapy for oropharynx cancer (OPC) is associated with
high rates of severe toxicities, shown to adversely impact patients' quality of life. Given …
high rates of severe toxicities, shown to adversely impact patients' quality of life. Given …
[HTML][HTML] Prospective in silico study of the feasibility and dosimetric advantages of MRI-guided dose adaptation for human papillomavirus positive oropharyngeal …
ASR Mohamed, H Bahig, M Aristophanous… - Clinical and translational …, 2018 - Elsevier
Purpose We aim to determine the feasibility and dosimetric benefits of a novel MRI-guided
IMRT dose-adaption strategy for human papillomavirus positive (HPV+) oropharyngeal …
IMRT dose-adaption strategy for human papillomavirus positive (HPV+) oropharyngeal …
Differential response rates to irradiation among patients with human papillomavirus positive and negative oropharyngeal cancer
AM Chen, J Li, LA Beckett, T Zhara, G Farwell… - The …, 2013 - Wiley Online Library
Abstract Objectives/Hypothesis: To evaluate the responsiveness of human papillomavirus
(HPV)‐positive and HPV‐negative oropharyngeal cancer to intensity‐modulated …
(HPV)‐positive and HPV‐negative oropharyngeal cancer to intensity‐modulated …
Inadequate target volume delineation and local–regional recurrence after intensity-modulated radiotherapy for human papillomavirus-positive oropharynx cancer
AM Chen, R Chin, P Beron, T Yoshizaki… - Radiotherapy and …, 2017 - Elsevier
Purpose To perform a spatial analysis of local–regional recurrences, in relation to
quantitative dose distribution, among patients treated by intensity-modulated radiotherapy …
quantitative dose distribution, among patients treated by intensity-modulated radiotherapy …
Dose and volume de-escalation for human papillomavirus–positive oropharyngeal cancer is associated with favorable posttreatment functional outcomes
CC Foster, TY Seiwert, E MacCracken, EA Blair… - International Journal of …, 2020 - Elsevier
Purpose To report functional outcomes for patients with human papillomavirus–positive
oropharyngeal cancer treated on a phase 2 protocol of risk-and induction chemotherapy …
oropharyngeal cancer treated on a phase 2 protocol of risk-and induction chemotherapy …
Randomized phase II study of physiologic MRI-directed adaptive radiation boost in poor prognosis head and neck cancer
Purpose: We conducted a randomized phase II multicenter clinical trial to test the hypothesis
that physiologic MRI-based radiotherapy (RT) dose escalation would improve the outcome …
that physiologic MRI-based radiotherapy (RT) dose escalation would improve the outcome …
[HTML][HTML] Target definition in MR-guided adaptive radiotherapy for head and neck cancer
M Ridder, CPJ Raaijmakers, FA Pameijer, R Bree… - Cancers, 2022 - mdpi.com
Simple Summary Adaptive radiotherapy for head and neck cancer has become more routine
due to an increase in imaging quality and improvement in radiation techniques. With the …
due to an increase in imaging quality and improvement in radiation techniques. With the …
[引用][C] Radiation dose de-escalation in HPV-positive oropharynx cancer: when will it be an acceptable standard of care?
A Chundury, S Kim - Journal of Clinical Oncology, 2021 - ascopubs.org
Human papillomavirus (HPV) is now the most common cause of oropharyngeal squamous
cell carcinoma (OPSCC) in the United States, with recent data suggesting that for every two …
cell carcinoma (OPSCC) in the United States, with recent data suggesting that for every two …
[HTML][HTML] Proton Image-guided radiation assignment for therapeutic escalation via selection of locally advanced head and neck cancer patients [PIRATES]: a phase I …
LV van Dijk, SJ Frank, Y Yuan, B Gunn… - Clinical and translational …, 2022 - Elsevier
Introduction Radiation dose-escalation for head and neck cancer (HNC) patients aiming to
improve cure rates is challenging due to the increased risk of unacceptable treatment …
improve cure rates is challenging due to the increased risk of unacceptable treatment …
[HTML][HTML] OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer
TY Seiwert, CC Foster, EA Blair, TG Karrison… - Annals of …, 2019 - Elsevier
Background Patients with HPV+ oropharyngeal squamous cell carcinoma were assigned to
dose and volume de-escalated radiotherapy (RT) or chemoradiotherapy (CRT) based on …
dose and volume de-escalated radiotherapy (RT) or chemoradiotherapy (CRT) based on …