Cancer Prevention and Therapy by Targeting Oxidative Stress Pathways

S Saha, L Saso, G Armagan - Molecules, 2023 - mdpi.com
Oxidative stress arises from the inadequate production of reactive oxygen species (ROS)
which couldn't be neutralized by antioxidant defense. Cells maintain this balance of oxidants …

Targeting Reactive Oxygen Species (ROS) for Cancer Therapy

H Mohan, Vandna, S Soni, S Syed - Handbook of Oxidative Stress in …, 2022 - Springer
Reactive oxygen species (ROS) are the highly reactive molecules that play vital roles in
cancer progression as well as in the regulation of important cellular pathways. Interestingly …

Oxidative stress and cancer: advances and challenges

S Prasad, SC Gupta, MK Pandey… - Oxidative medicine and …, 2016 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) constantly generated inside the body are required to drive
regulatory pathways and are also a cause for several pathological conditions including …

Targeting oxidative stress in cancer: what is new in the prevention, diagnostic, treatment and prognostic strategies?

Q Liao, ZB Wang, SMSC Cadena - Frontiers in Pharmacology, 2023 - frontiersin.org
Cancer is one of the leading causes of death worldwide, accounting for about 10 million
deaths in 2020. Its incidence increases yearly, compromising individuals, families, and …

[HTML][HTML] Harnessing oxidative stress as an innovative target for cancer therapy

L Postovit, C Widmann, P Huang… - Oxidative medicine and …, 2018 - ncbi.nlm.nih.gov
One of the hallmarks of cancer is the deregulation of cellular energetics [1]. This allows
cancer cells to proliferate and survive in microenvironments that would lead to the death of a …

[HTML][HTML] The interplay between reactive oxygen species and antioxidants in cancer progression and therapy: a narrative review

OH Bekhet, ME Eid - Translational Cancer Research, 2021 - ncbi.nlm.nih.gov
Objective To unveil the role of reactive oxygen species (ROS) and antioxidants in signaling
and involvement in cancer progression and therapy. Background Cancer is considered one …

Oxidative stress and antioxidants in disease and cancer: a review

RK Gupta, AK Patel, N Shah… - Asian Pacific journal …, 2014 - journal.waocp.org
Reactive oxygen species (ROS), highly reactive molecules, are produced by living
organisms as a result ofnormal cellular metabolism and environmental factors, and can …

[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy

Y Wang, H Qi, Y Liu, C Duan, X Liu, T Xia, D Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

Paradox role of oxidative stress in cancer: State of the art

C Domenicotti, B Marengo - Antioxidants, 2022 - mdpi.com
The modulation of oxidative stress is essential for the maintenance of redox homeostasis in
healthy and cancer cells. In fact, although cancer cells are characterized by the …

Role of oxygen free radicals in cancer development and treatment

J Pourahmad, A Salimi, E Seydi - Free radicals and diseases, 2016 - books.google.com
It is well known that species derived from oxygen are cytotoxic and are involved in the
etiology of cancer. Several carcinogens during metabolism exert their effect by producing …