Impact of direct disk-diffusion testing on time to optimal antibiotic therapy

TA Jhaveri, A Taqi, JC Pearson… - … Stewardship & Healthcare …, 2023 - cambridge.org
We evaluated the impact of preliminary blood-culture antibiotic susceptibility testing on time
to optimal antibiotic therapy in a cohort of 503 patients with monomicrobial bloodstream …

Predictive value of direct disk diffusion testing from positive blood cultures in a children's hospital and its utility in antimicrobial stewardship

TJ Savage, S Rao, J Joerger, A Ozonoff… - Journal of clinical …, 2021 - Am Soc Microbiol
Accurate and early susceptibility results could reduce overuse of broad-spectrum antibiotics
for empirical treatment of bacteremia. Direct disk diffusion testing (dDD) using …

Rapid Disc Diffusion Susceptibility Testing Directly From Blood Cultures With Gram-Negative Bacilli is an Accurate Inexpensive Tool to Facilitate Prompt Antibiotic …

H Saito, K Evans, E Peterson… - Open Forum Infectious …, 2016 - academic.oup.com
Background. Current national strategy addresses antibiotic stewardship in order to decrease
selection of antibiotic resistance and aims to advance the development and use of rapid …

The Performance of Direct Disk Diffusion for Community Acquired Bacteremia due to Gram‐Negative Bacilli and Its Impact on Physician Treatment Decisions

P Daley, A Comerford, J Umali… - Canadian Journal of …, 2016 - Wiley Online Library
Background. Direct disk diffusion susceptibility testing provides faster results than standard
microtitre susceptibility. The direct result may impact patient outcome in sepsis if it is …

Direct method to determine the antibiotic susceptibility of rapidly growing blood pathogens

DL Wegner, CR Mathis, TR Neblett - Antimicrobial Agents and …, 1976 - Am Soc Microbiol
Rapidly Growing Blood Pathogens Page 1 ANTIMICROBIAL AGENTS AND
CHEMOTHERAPY, May 1976, p. 861-862 Copyright C 1976 American Society for …

Stop waiting for tomorrow: disk diffusion performed on early growth is an accurate method for antimicrobial susceptibility testing with reduced turnaround time

DM Webber, MA Wallace… - Journal of clinical …, 2022 - Am Soc Microbiol
Disk diffusion is a slow but reliable standard method for measuring the antimicrobial
susceptibility of microorganisms. Our objective was to improve the turnaround time for this …

[PDF][PDF] Implementation of the CLSI method for direct disk diffusion testing from positive blood cultures

AN Schuetz, A Bobenchik… - CLSI AST News Update, 2022 - community.clsi.org
The CLSI AST Subcommittee has developed and published breakpoints for direct blood
culture disk diffusion (DD) testing of several antimicrobial agents for Enterobacterales and …

Time to positivity of blood cultures supports antibiotic de-escalation at 48 hours

J Pardo, KP Klinker, SJ Borgert… - Annals of …, 2014 - journals.sagepub.com
Background: Appropriate de-escalation of empirical antimicrobial therapy is a fundamental
component of antimicrobial stewardship. Concern for the late detection of bloodstream …

Direct-from-blood-culture disk diffusion to determine antimicrobial susceptibility of Gram-negative bacteria: preliminary report from the Clinical and Laboratory …

S Chandrasekaran, A Abbott, S Campeau… - Journal of clinical …, 2018 - Am Soc Microbiol
The performance of a disk diffusion test using broth from positive blood cultures as inoculum
(direct disk diffusion [dDD]) was evaluated for a collection of 20 challenge isolates of …

The impact of the first notification of positive blood cultures on antibiotic therapy: a one‐year survey

HC Schønheyder, T Højbjerg - Apmis, 1995 - Wiley Online Library
The impact on antibiotic therapy of the first notification of positive blood cultures was
assessed for 735 episodes of bacteraemia detected during 1992 in the County of Northern …