Synergistic effects of enriched environment and task-specific reach training on poststroke recovery of motor function
MS Jeffers, D Corbett - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Reach training in concert with environmental enrichment
provides functional benefits after experimental stroke in rats. The present study extended …
provides functional benefits after experimental stroke in rats. The present study extended …
Enriched environment promotes efficiency of compensatory movements after cerebral ischemia in rats
Rehabilitation therapy is known to drive motor improvement in stroke patients. However, the
interplay of functional recovery and compensation in postischemic motor behavior is poorly …
interplay of functional recovery and compensation in postischemic motor behavior is poorly …
[HTML][HTML] Task-specific motor rehabilitation therapy after stroke improves performance in a different motor task: translational evidence
While the stroke survivor with a motor deficit strives for recovery of all aspects of daily life
movements, neurorehabilitation training is often task specific and does not generalize to …
movements, neurorehabilitation training is often task specific and does not generalize to …
The effects of repeated rehabilitation “tune-ups” on functional recovery after focal ischemia in rats
J Clarke, H Mala, V Windle… - … and neural repair, 2009 - journals.sagepub.com
Background. For most stroke survivors, rehabilitation therapy is the only treatment option
available. The beneficial effects of early rehabilitation on neuroplasticity and functional …
available. The beneficial effects of early rehabilitation on neuroplasticity and functional …
A critical threshold of rehabilitation involving brain-derived neurotrophic factor is required for poststroke recovery
CL MacLellan, MB Keough… - … and neural repair, 2011 - journals.sagepub.com
Background. Enriched rehabilitation (ER; environmental enrichment plus skilled reaching)
improves recovery after middle cerebral artery occlusion (MCAo) in rats. Fundamental …
improves recovery after middle cerebral artery occlusion (MCAo) in rats. Fundamental …
Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury
J Biernaskie, D Corbett - Journal of Neuroscience, 2001 - Soc Neuroscience
Chronic impairment of forelimb and digit movement is a common problem after stroke that is
resistant to therapy. Previous studies have demonstrated that enrichment improves …
resistant to therapy. Previous studies have demonstrated that enrichment improves …
Efficacy of rehabilitative experience declines with time after focal ischemic brain injury
J Biernaskie, G Chernenko, D Corbett - Journal of Neuroscience, 2004 - Soc Neuroscience
To maximize the effectiveness of rehabilitative therapies after stroke, it is critical to determine
when the brain is most responsive (ie, plastic) to sensorimotor experience after injury and to …
when the brain is most responsive (ie, plastic) to sensorimotor experience after injury and to …
An enriched environment improves sensorimotor function post-ischemic stroke
H Janssen, J Bernhardt, JM Collier… - … and neural repair, 2010 - journals.sagepub.com
Objective. An enriched environment (EE) refers to conditions that facilitate or enhance
sensory, cognitive, motor, and social stimulation relative to standard (laboratory) conditions …
sensory, cognitive, motor, and social stimulation relative to standard (laboratory) conditions …
Training and stimulation in post stroke recovery brain reorganization
In both animal and clinical studies, training or rehabilitation increases cortical representation
with subsequent functional recovery, whereas a lack of rehabilitation or training decreases …
with subsequent functional recovery, whereas a lack of rehabilitation or training decreases …
Does stroke rehabilitation really matter? Part B: an algorithm for prescribing an effective intensity of rehabilitation
MS Jeffers, S Karthikeyan… - … and neural repair, 2018 - journals.sagepub.com
Background. The proportional recovery rule suggests that current rehabilitation practices
may have limited ability to influence stroke recovery. However, the appropriate intensity of …
may have limited ability to influence stroke recovery. However, the appropriate intensity of …
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