Accumulating evidence indicates integration of dopamine function with metabolic signals,
highlighting a potential role for dopamine in energy balance, frequently construed as …

In neuroscience literature, dopamine is often considered as a pleasure chemical of the
brain. Dopaminergic neurons respond to rewarding stimuli which include primary rewards …

Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …

This review examines human feeding behavior in light of psychological motivational theory
and highlights the importance of midbrain dopamine (DA). Prospective evidence of both …

Recent work has implicated dopaminergic mechanisms in overeating and obesity with some
researchers suggesting parallels between the dopamine dysregulation associated with …

There is a well-established literature linking obesity to altered dopamine signaling and brain
response to food-related stimuli. Neuroimaging studies frequently report enhanced …

Energy deficit is characterised by high ghrelin levels, and low leptin and insulin levels and
we suggest that this provides a metabolic signature sensed by the brain to increase …

Obesity is a major public health problem. The increasing number of obese individuals in the
US adds urgency to the efforts to understand the mechanisms underlying pathological …

There is increasing evidence demonstrating that reward-related motivational food intake is
closely connected with the brain's homeostatic system of energy balance and that this …

Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …