Objectives The objective of this study was to describe the population pharmacokinetics of
cefazolin in plasma and the interstitial fluid of subcutaneous tissue of post-trauma critically ill …

Introduction Cefazolin is commonly used to treat complicated skin and soft tissue infections
(cSSTI) caused by methicillin-susceptible Staphylococcus aureus (MSSA) and …

Background. Perioperative administration of cefazolin reduces the incidence of
perioperative infections. Intraoperative re-dosing of cefazolin is commonly given between 2 …

Cefazolin, a first-generation cephalosporin with activity against methicillin-susceptible
Staphylococcus aureus and streptococci, is often used to treat lower limb infections caused …

The objective of this study was to evaluate the steady state pharmacokinetics and
pharmacodynamics of cefazolin in patients with a high body weight. Cefazolin was …

Objectives As morbidly obese patients are prone to surgical site infections, adequate blood
and subcutaneous tissue concentrations of prophylactic antibiotic agents during surgery are …

Background The relative distribution of cefazolin into the cerebrospinal fluid (CSF) remains
debated. Determining the distribution of cefazolin into the CSF in noninfected adults may …

Objectives Cefazolin is one of curative treatments for infections due to methicillin-sensitive
Staphylococcus aureus (MSSA). Both growth and critical illness may impact the …

Optimal dosing of continuous-infusion cefazolin can be challenging in patients being treated
for bacteremia or infective endocarditis. The aim of this work is to describe and analyze the …

Background: Surgical-site infection is a common postoperative nosocomial infection.
Surgeons frequently treat operative patients with protective antibiotics and often choose …