Expression of the B‐cell antigen receptor (BCR) is essential not only for the development but
also for the maintenance of mature B cells. Similarly, many B‐cell lymphomas, including …

The BCR consists of surface-bound Ig and a heterodimeric signaling unit comprised of
CD79A and CD79B. Upon cognate Ag recognition, the receptor initiates important signals …

The transcriptional repressor B cell lymphoma 6 (BCL6) controls a large transcriptional
network that is required for the formation and maintenance of germinal centers (GC). GC B …

The binding of CD40 ligand on activated T cells to CD40 on resting B cells induces the
expression of costimulatory molecules B7-1 (CD80) and B7-2 (CD86). The induction of B7 …

We used clustered regularly interspaced short palindromic repeats/Cas9-mediated genomic
modification to investigate B-cell receptor (BCR) signaling in cell lines of diffuse large B-cell …

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin
lymphomas worldwide and is characterized by a high diversity of genetic and molecular …

The B cell lymphoma 6 (BCL6) transcriptional repressor is a master regulator of the germinal
center (GC) B cell program, required for their unique proliferative and stress tolerant …

BCL6 is a transcriptional repressor required for mature B-cell germinal center (GC) formation
and implicated in lymphomagenesis. BCL6's physiologic function is only partially known …

Burkitt's lymphoma (BL) is a highly proliferative B-cell neoplasm and is treated with intensive
chemotherapy that, because of its toxicity, is often not suitable for the elderly or for patients …

Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma and can be
separated into two subtypes based upon molecular features with similarities to germinal …