[HTML][HTML] Modeling 3D facial shape from DNA
P Claes, DK Liberton, K Daniels, KM Rosana… - PLoS …, 2014 - journals.plos.org
Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …
used spatially dense quasi-landmarks to measure face shape in population samples with …
Genome-wide mapping of global-to-local genetic effects on human facial shape
Genome-wide association scans of complex multipartite traits like the human face typically
use preselected phenotypic measures. Here we report a data-driven approach to …
use preselected phenotypic measures. Here we report a data-driven approach to …
Human facial shape and size heritability and genetic correlations
JB Cole, M Manyama, JR Larson, DK Liberton… - Genetics, 2017 - academic.oup.com
The human face is an array of variable physical features that together make each of us
unique and distinguishable. Striking familial facial similarities underscore a genetic …
unique and distinguishable. Striking familial facial similarities underscore a genetic …
A genome-wide association study identifies five loci influencing facial morphology in Europeans
Inter-individual variation in facial shape is one of the most noticeable phenotypes in
humans, and it is clearly under genetic regulation; however, almost nothing is known about …
humans, and it is clearly under genetic regulation; however, almost nothing is known about …
Genome-wide association study reveals multiple loci influencing normal human facial morphology
JR Shaffer, E Orlova, MK Lee, EJ Leslie… - PLoS …, 2016 - journals.plos.org
Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet
little is known about how specific genetic variants relate to the phenotypic expression of …
little is known about how specific genetic variants relate to the phenotypic expression of …
Let's face it—complex traits are just not that simple
The idea that we can reconstruct a human face from a DNA sample has great appeal: DNA
from a crime scene could be used to create a facial image of a suspect; the faces of …
from a crime scene could be used to create a facial image of a suspect; the faces of …
A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation
To characterize the genetic basis of facial features in Latin Americans, we performed a
genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark …
genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark …
Novel genetic loci affecting facial shape variation in humans
The human face represents a combined set of highly heritable phenotypes, but knowledge
on its genetic architecture remains limited, despite the relevance for various fields. A series …
on its genetic architecture remains limited, despite the relevance for various fields. A series …
Decoding the human face: progress and challenges in understanding the genetics of craniofacial morphology
Variations in the form of the human face, which plays a role in our individual identities and
societal interactions, have fascinated scientists and artists alike. Here, we review our current …
societal interactions, have fascinated scientists and artists alike. Here, we review our current …
Discriminating power of localized three-dimensional facial morphology
P Hammond, TJ Hutton, JE Allanson, B Buxton… - The American Journal of …, 2005 - cell.com
Many genetic syndromes involve a facial gestalt that suggests a preliminary diagnosis to an
experienced clinical geneticist even before a clinical examination and genotyping are …
experienced clinical geneticist even before a clinical examination and genotyping are …