The bacterial mobile resistome transfer network connecting the animal and human microbiomes

Y Hu, X Yang, J Li, N Lv, F Liu, J Wu… - Applied and …, 2016 - Am Soc Microbiol
Horizontally acquired antibiotic resistance genes (ARGs) in bacteria are highly mobile and
have been ranked as principal risk resistance determinants. However, the transfer network …

[HTML][HTML] Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

The antibiotic resistome: gene flow in environments, animals and human beings

Y Hu, GF Gao, B Zhu - Frontiers of medicine, 2017 - Springer
The antibiotic resistance is natural in bacteria and predates the human use of antibiotics.
Numerous antibiotic resistance genes (ARGs) have been discovered to confer resistance to …

[HTML][HTML] Mobilization of antibiotic resistance: are current approaches for colocalizing resistomes and mobilomes useful?

IB Slizovskiy, K Mukherjee, CJ Dean… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial resistance (AMR) poses a global human and animal health threat, and
predicting AMR persistence and transmission remains an intractable challenge. Shotgun …

[HTML][HTML] Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance

K Lee, DW Kim, DH Lee, YS Kim, JH Bu, JH Cha… - Microbiome, 2020 - Springer
Background The impact of human activities on the environmental resistome has been
documented in many studies, but there remains the controversial question of whether the …

Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome

A Crits-Christoph, HA Hallowell, K Koutouvalis… - Gut …, 2022 - Taylor & Francis
ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …

[HTML][HTML] Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes

JS Inda-Díaz, D Lund, M Parras-Moltó, A Johnning… - Microbiome, 2023 - Springer
Background Bacterial communities in humans, animals, and the external environment
maintain a large collection of antibiotic resistance genes (ARGs). However, few of these …

[HTML][HTML] Evidence for wastewaters as environments where mobile antibiotic resistance genes emerge

F Berglund, S Ebmeyer, E Kristiansson… - Communications …, 2023 - nature.com
The emergence and spread of mobile antibiotic resistance genes (ARGs) in pathogens have
become a serious threat to global health. Still little is known about where ARGs gain mobility …

Antibiotic treatment drives the diversification of the human gut resistome

J Li, EA Rettedal, E van der Helm… - Genomics …, 2019 - academic.oup.com
Despite the documented antibiotic-induced disruption of the gut microbiota, the impact of
antibiotic intake on strain-level dynamics, evolution of resistance genes, and factors …

[HTML][HTML] Platforms for elucidating antibiotic resistance in single genomes and complex metagenomes

CL Gupta, RK Tiwari, E Cytryn - Environment international, 2020 - Elsevier
Antibiotic or antimicrobial resistance (AR) facilitated by the vertical and/or horizontal transfer
of antibiotic resistance genes (ARGs), is a serious global health challenge. While …