New challenges for pharmaceutical formulations and drug delivery systems characterization using isothermal titration calorimetry
K Bouchemal - Drug discovery today, 2008 - Elsevier
Long viewed as the 'method of choice'for characterizing thermodynamics and stoichiometry
of molecular interactions, with high sensitivity, isothermal titration calorimetry (ITC) has been …
of molecular interactions, with high sensitivity, isothermal titration calorimetry (ITC) has been …
Survey of the year 2009: applications of isothermal titration calorimetry
RJ Falconer, BM Collins - Journal of molecular recognition, 2011 - Wiley Online Library
Isothermal titration calorimetry (ITC) is now an established and invaluable method for
determining the thermodynamic constants, association constant and stoichiometry of …
determining the thermodynamic constants, association constant and stoichiometry of …
Isothermal titration calorimetry (ITC) as a promising tool in pharmaceutical nanotechnology
IDL Cavalcanti, FHX Junior, NSS Magalhães… - International Journal of …, 2023 - Elsevier
Isothermal titration calorimetry (ITC) is a technique for evaluating the thermodynamic profiles
of connection between two molecules, allowing the experimental design of nanoparticles …
of connection between two molecules, allowing the experimental design of nanoparticles …
Application of isothermal titration calorimetry as a tool to study natural product interactions
O Callies, AH Daranas - Natural product reports, 2016 - pubs.rsc.org
Covering: up to February 2015 Over the past twenty-five years, isothermal titration
calorimetry (ITC) has become a potent tool for the study a great variety of molecular …
calorimetry (ITC) has become a potent tool for the study a great variety of molecular …
Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions
MH Chiu, EJ Prenner - Journal of Pharmacy and Bioallied …, 2011 - journals.lww.com
Abstract Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the
thermotropic properties of many different biological macromolecules and extracts. Since its …
thermotropic properties of many different biological macromolecules and extracts. Since its …
Thermodynamic properties of hydroxypropyl-β-cyclodextrin/guest interaction: a survey of recent studies
F D'Aria, B Pagano, C Giancola - Journal of Thermal Analysis and …, 2022 - Springer
For many years, cyclodextrins (CDs) have been the object of attention for their capability of
improving the stability, solubility and bioavailability of numerous molecules of interest …
improving the stability, solubility and bioavailability of numerous molecules of interest …
Isothermal titration calorimetry: practical approaches and current applications in soft matter
Isothermal Titration Calorimetry (ITC) elucidates the thermodynamic profile (ΔH, ΔS, ΔG, Ka,
and stoichiometry) of binding and dissociation reactions in solution. While ITC has primarily …
and stoichiometry) of binding and dissociation reactions in solution. While ITC has primarily …
A survey of the year 2007 literature on applications of isothermal titration calorimetry
S Bjelić, I Jelesarov - Journal of Molecular Recognition, 2008 - Wiley Online Library
Elucidation of the energetic principles of binding affinity and specificity is a central task in
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …
How to conduct and interpret ITC experiments accurately for cyclodextrin–guest interactions
K Bouchemal, S Mazzaferro - Drug Discovery Today, 2012 - Elsevier
Isothermal titration calorimetry (ITC) is one of the most interesting methods for the
characterization of the interaction mechanisms of cyclodextrins (CDs) with drugs. In this …
characterization of the interaction mechanisms of cyclodextrins (CDs) with drugs. In this …
Making cool drugs hot: isothermal titration calorimetry as a tool to study binding energetics.
GA Holdgate - Biotechniques, 2001 - europepmc.org
Characterization of the thermodynamics of binding interactions is important in improving our
understanding of bimolecular recognition and forms an essential part of the rational drug …
understanding of bimolecular recognition and forms an essential part of the rational drug …