Alterations in neutrophil extracellular traps is associated with the degree of decompensation of liver cirrhosis

JM Agraz-Cibrian, JE Segura-Ortega… - The Journal of Infection …, 2016 - jidc.org
Introduction: Liver cirrhosis (LC) constitutes one of the main 10 causes of death worldwide.
LC has a characteristic asymptomatic compensated phase followed by a progressive …

Impaired neutrophil extracellular traps and inflammatory responses in the peritoneal fluid of patients with liver cirrhosis

JM Agraz‐Cibrián, V Delgado‐Rizo… - Scandinavian …, 2018 - Wiley Online Library
Liver cirrhosis (LC) is an inflammatory process associated with impaired functions in
adaptive and innate immune responses at both systemic and local levels, also referred as …

[HTML][HTML] Phagocytic and oxidative burst activity of neutrophils in the end stage of liver cirrhosis

A Panasiuk, J Wysocka, E Maciorkowska… - World Journal of …, 2005 - ncbi.nlm.nih.gov
METHODS: In 45 patients with advanced postalcoholic liver cirrhosis (aged 45±14 years)
and in 25 healthy volunteers (aged 38±5 years), the percentage of phagocytizing cells after …

[HTML][HTML] Circulating neutrophil anti-pathogen dysfunction in liver cirrhosis

I Balazs, V Stadlbauer - JHEP Reports, 2023 - Elsevier
Neutrophils are the largest population of leucocytes and are among the first cells of the
innate immune system to fight against intruding pathogens. Cirrhotic patients' neutrophils …

[PDF][PDF] Generation of neutrophil extracellular traps in patients with acute liver failure is associated with poor outcome

FA von Meijenfeldt, RT Stravitz, J Zhang… - …, 2022 - Wiley Online Library
Abstract Background and Aims Acute liver failure (ALF) is characterized by significant
changes in the hemostatic system and by systemic inflammation. The formation of neutrophil …

Identification of neutrophil extracellular traps in the blood of patients with systemic inflammatory response syndrome

S Hamaguchi, T Hirose, Y Akeda… - Journal of …, 2013 - journals.sagepub.com
Objective Neutrophils are able to form 'neutrophil extracellular traps'(NETs), which they use
to trap and kill pathogens such as bacteria and fungi at the foci of infection. This …

Role for neutrophil extracellular traps (NETs) and platelet aggregation in early sepsis-induced hepatic dysfunction

K Sakurai, T Miyashita, M Okazaki, T Yamaguchi… - in vivo, 2017 - iv.iiarjournals.org
Background/Aim: Severe sepsis is associated with high morbidity and mortality rates.
Inflammation and coagulation play pivotal roles in the pathogenesis of sepsis leading to …

[HTML][HTML] Ascites' neutrophil function is significantly impaired in patients with decompensated cirrhosis but can be restored by autologous plasma incubation

C Engelmann, C Becker, A Boldt, T Herta, A Boehlig… - Scientific Reports, 2016 - nature.com
Systemic immune cell dysfunction is a typical feature of liver diseases and increases the risk
of bacterial infection, especially spontaneous bacterial peritonitis. We evaluated functional …

The severity of circulating neutrophil dysfunction in patients with cirrhosis is associated with 90‐day and 1‐year mortality

NJ Taylor, GK Manakkat Vijay… - Alimentary …, 2014 - Wiley Online Library
Background Patients with cirrhosis are susceptible to sepsis, pre‐disposing to the
development of encephalopathy, bleeding and organ dysfunction with associated high …

Evidence of neutrophil functional defect despite inflammation in stable cirrhosis

G Tritto, Z Bechlis, V Stadlbauer, N Davies… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Deranged neutrophil function in alcoholic hepatitis has been
shown to be transmissible to normal neutrophils by patient plasma. The aims of this study …