Among the different families of plant alkaloids,(-)-roemerine, an aporphine type, was recently
shown to possess significant antibacterial activity in Escherichia coli. Based on the …

Discovery of new antibacterials with novel mechanisms is important to counteract the
ingenious resistance mechanisms of bacteria. In this connection, omics-guided drug …

Plant-derived substances have regained interest in the fight against antibiotic resistance
owing to their distinct antimicrobial mechanisms and multi-target properties. With the recent …

Staphylococcus aureus is one of the most frequently occurring hospital-and community-
associated pathogenic bacteria featuring high morbidity and mortality. The occurrence of …

Combining pentamidine with Gram-positive-targeting antibiotics has been proven to be a
promising strategy for treating infections from Gram-negative bacteria (GNB). However …

Antibiotics can be classified based upon drug-target interaction and lethality. Bactericidal
drugs, which target cell wall/membrane synthesis, DNA replication and repair or protein …

Antibiotics are certainly beneficial to treat the bacterial infection. However, inappropriate use
puts patients at danger for avoidable adverse drug reactions. This inappropriate use …

Methylrhodomelol (1) is a bromophenol from the red alga Vertebrata lanosa that has been
associated with antimicrobial properties. The aim of the current study was, therefore, to …

Background Plants are traditionally used for medicinal treatment of numerous human
disorders including infectious diseases caused by microorganisms. Due to the increasing …

Reuterin is an antimicrobial compound produced by Lactobacillus reuteri, and has been
proposed to mediate, in part, the probiotic health benefits ascribed to this micro-organism …