In vitro evaluation of the antiparasitic activity of p-coumaric acid prenylated derivatives

T Vieira, J Barco, L Paula, P Félix, J Bastos… - 2024 - chemrxiv.org
We have evaluated eight p-coumaric acid prenylated derivatives in vitro for their
antileishmanial activity against Leishmania amazonensis promastigotes and their …

In vitro Evaluation of the Antileishmanial and Antischistosomal Activities of p‐Coumaric Acid Prenylated Derivatives

TM Vieira, JG Barco, LAL Paula… - Chemistry & …, 2024 - Wiley Online Library
We have evaluated eight p‐coumaric acid prenylated derivatives in vitro for their
antileishmanial activity against Leishmania amazonensis promastigotes and their …

[HTML][HTML] Synthesis and biological evaluation against Leishmania amazonensis of a series of alkyl-substituted benzophenones

CM Maciel-Rezende, L De Almeida, ÉDM Costa… - Bioorganic & medicinal …, 2013 - Elsevier
Nine O-alkyl and O-prenyl derivatives were synthesized from commercial 2, 4-
dihydroxybenzophenone, 4, e4, 4′-dihydroxybenzophenone and were evaluated for their …

Synthesis and antiparasitic activity against Trypanosoma cruzi and Leishmania amazonensis of chlorinated 1, 7-and 1, 8-naphthyridines

L Everson da Silva, A Carlos Joussef… - Letters in Drug …, 2007 - ingentaconnect.com
The leishmanicidal and trypanocidal activities of chlorinated 1, 7-and 1, 8-naphthyridines
were evaluated against cultured of L. amazonensis promastigote and T. cruzi epimastigote …

[HTML][HTML] Anti-leishmanial and structure-activity relationship of ring substituted 3-phenyl-1-(1, 4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives

A Burguete, Y Estevez, D Castillo… - Memorias do Instituto …, 2008 - SciELO Brasil
A series of ring substituted 3-phenyl-1-(1, 4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one
derivatives were synthesized and tested for in vitro leishmanicidal activity against …

Synthesis and biological evaluation of some 6-substituted purines

FG Braga, ES Coimbra, M de Oliveira Matos… - European journal of …, 2007 - Elsevier
We report herein the synthesis and the in vitro antileishmanial evaluation of a series of 6-
substituted purines. The most active compounds against Leishmania amazonensis …

Synthetic derivatives of curcumin and their activity against Leishmania amazonensis

D de CF Gomes, LV Alegrio, MEF de Lim… - …, 2002 - thieme-connect.com
In a previous work, the in vitro and in vivo activity of a series of diarylheptanoid derivatives
against Leishmania amazonensis has been described. Based on the promising results, ten …

[HTML][HTML] Efficacy of a diarylheptanoid derivative against Leishmania amazonensis

LV Alves, RM Temporal, L Cysne-Finkelstein… - Memórias do Instituto …, 2003 - SciELO Brasil
The activity of several diarylheptanoid derivatives (curcuminoids) was previously evaluated
against Leishmania amazonensis promastigotes and among them the most active …

Novel prenyloxy chalcones as potential leishmanicidal and trypanocidal agents: design, synthesis and evaluation

JC Espinoza-Hicks, KF Chacón-Vargas… - European Journal of …, 2019 - Elsevier
The available drugs for treating Leishmaniasis and American trypanosomiasis have high
toxicity and multiple side effects, among other problems. More effective and less toxic …

An effective diaryl derivative against Leishmania amazonensis and its influence on the parasite X macrophage interaction

LV Alves, L Cysne-Finkelstein… - Journal of Enzyme …, 2004 - Taylor & Francis
The activity of several diarylheptanoid derivatives (curcuminoids) was previously evaluated
against Leishmania amazonensis promastigotes and among them the most active …