Nephrotoxicity (NT) is a renal-specific situation caused by different toxins and drugs like non-
steroidal anti-inflammatory drugs (NSAIDs). NSAIDs like diclofenac (DCF) lead to glomerular …

Hesperidin is derived from citrus fruits among other plants. Hesperidin was methylated to
increase its solubility, generating hesperidin methyl chalcone (HMC), an emerging flavonoid …

Aims Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and effective anti-
inflammatories despite the well-known side effects such as gastrointestinal damage, acute …

Background/Aim Diclofenac (DIC) is a Nonsteroidal anti-inflammatory drug (NSAID) and
consumption of this drug creates side effects such as renal injury. The purpose of this work …

Acute kidney injury (AKI) represents a complex clinical condition associated with significant
morbidity and mortality. Approximately, 19–33% AKI episodes in hospitalized patients are …

Background Folic acid (FA)-induced acute renal injury (AKI) is a commonly and highly
reproducible model used to study AKI. The current study aims to evaluate the possible …

Diabetic nephropathy (DN) is a serious diabetic complication with renal hypertrophy and
expansion of extracellular matrices in renal fibrosis. Epithelial-to-mesenchymal transition …

Cyclosporine is one of the main immunosuppressive agents used in the treatment of
autoimmune diseases or transplantation. Despite the favorable effects, cyclosporine …

Gentamicin (GNT) is a potent aminoglycoside antibiotic widely used to treat life-threatening
bacterial infections. We aim to investigate the potential protective effect of ursodeoxycholic …

Oxidative stress and inflammatory responses are closely implicated in the progression of
renal interstitial fibrosis, thereby leading to chronic kidney disease. Cryptotanshinone (CTS) …