This study identifies by microautoradiography activated microglia/macrophages as the main
cell type expressing the peripheral benzodiazepine binding site (PBBS) at sites of active …

Activated glial cells are implicated in regulating and effecting the immune response that
occurs within the CNS as part of multiple sclerosis (MS) and its animal model experimental …

Increased binding of a ligand for the peripheral benzodiazepine binding receptor is currently
used in PET studies as an in vivo measurement of inflammation in diseases like multiple …

The peripheral benzodiazepine receptor (PBR) has been used as a sensitive marker to
visualize and measure glial cell activation associated with various forms of brain injury and …

Activated microglia are an important feature of many neurological diseases and can be
imaged in vivo using 1‐(2‐chlorophenyl)‐N‐methyl‐N‐(1‐methylpropyl)‐3 …

With the purpose of demonstrating the use of positron emission tomography (PET) and
radiolabelled glia markers to indicate regional cerebral damage, we measured with PET in …

Microglia constitute the primary resident immune surveillance cell in the brain and are
thought to play a significant role in the pathogenesis of several neurodegenerative …

11C-(R)-PK11195 is a PET radiotracer for the quantification of peripheral benzodiazepine
binding sites (PBBSs). The PBBS is a consistent marker of activated microglia, and 11C-(R) …

Human gliomas were imaged in vivo using ligands for the peripheral‐type benzodiazepine
site (or ω3 binding site) and positron emission tomography (PET). Although gliomas have a …

Activated microglia are involved in the immune response of multiple sclerosis (MS). The
peripheral benzodiazepine receptor (PBR) is expressed on microglia and up‐regulated after …