Bioinspired multivalent DNA network for capture and release of cells
Capture and isolation of flowing cells and particulates from body fluids has enormous
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices
Isolation of circulating tumor cells (CTCs) from peripheral blood or cancer cells from bone
marrow has significant applications in cancer diagnosis, therapy monitoring, and drug …
marrow has significant applications in cancer diagnosis, therapy monitoring, and drug …
DNA nanolithography enables a highly ordered recognition interface in a microfluidic chip for the efficient capture and release of circulating tumor cells
J Zhang, B Lin, L Wu, M Huang, X Li… - Angewandte …, 2020 - Wiley Online Library
Microfluidic chips with nano‐scale structures have shown great potential, but the fabrication
and cost issues restrict their application. Herein, we propose a conceptually new “DNA …
and cost issues restrict their application. Herein, we propose a conceptually new “DNA …
Encapsulation and release of living tumor cells using hydrogels with the hybridization chain reaction
Circulating tumor cells (CTCs) enable noninvasive liquid biopsy and identification of cancer.
Various approaches exist for the capture and release of CTCs, including microfluidic …
Various approaches exist for the capture and release of CTCs, including microfluidic …
Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device
Circulating tumor cells (CTC) in the peripheral blood could provide important information for
diagnosis of cancer metastasis and monitoring treatment progress. However, CTC are …
diagnosis of cancer metastasis and monitoring treatment progress. However, CTC are …
Accurate isolation of circulating tumor cells via a heterovalent DNA framework recognition element-functionalized microfluidic chip
Y Liu, Z Lin, Z Zheng, Y Zhang, L Shui - ACS sensors, 2022 - ACS Publications
Detection of circulating tumor cells (CTCs) has provided a noninvasive and efficient
approach for early diagnosis, treatment, and prognosis of cancer. However, efficient capture …
approach for early diagnosis, treatment, and prognosis of cancer. However, efficient capture …
T lymphocyte-captured DNA network for localized immunotherapy
C Yao, C Zhu, J Tang, J Ou, R Zhang… - Journal of the American …, 2021 - ACS Publications
The efficient isolation of immune cells with high purity and low cell damage is important for
immunotherapy and remains highly challenging. We herein report a cell capture DNA …
immunotherapy and remains highly challenging. We herein report a cell capture DNA …
Double rolling circle amplification generates physically cross-linked DNA network for stem cell fishing
C Yao, H Tang, W Wu, J Tang, W Guo… - Journal of the …, 2020 - ACS Publications
Stem cells have been widely studied in cell biology and utilized in cell-based therapies, and
fishing stem cells from marrow is highly challenging due to the ultralow content. Herein, a …
fishing stem cells from marrow is highly challenging due to the ultralow content. Herein, a …
Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells
Y Xu, JA Phillips, J Yan, Q Li, ZH Fan… - Analytical chemistry, 2009 - ACS Publications
The ability to diagnose cancer based on the detection of rare cancer cells in blood or other
bodily fluids is a significant challenge. To address this challenge, we have developed a …
bodily fluids is a significant challenge. To address this challenge, we have developed a …
Enrichment of cancer cells using aptamers immobilized on a microfluidic channel
This work describes the development and investigation of an aptamer modified microfluidic
device that captures rare cells to achieve a rapid assay without pretreatment of cells. To …
device that captures rare cells to achieve a rapid assay without pretreatment of cells. To …