Dual role of astrocytes in perinatal asphyxia injury and neuroprotection

J Romero, J Muñiz, TL Tornatore, M Holubiec… - Neuroscience …, 2014 - Elsevier
Perinatal asphyxia represents an important cause of severe neurological deficits including
delayed mental and motor development, epilepsy, major cognitive deficits and blindness …

Metabolic changes following perinatal asphyxia: role of astrocytes and their interaction with neurons

T Logica, S Riviere, MI Holubiec, R Castilla… - Frontiers in aging …, 2016 - frontiersin.org
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits
including delayed mental and motor development, epilepsy, major cognitive deficits and …

Astrocyte responses after neonatal ischemia: the yin and the yang

S Villapol, A Gelot, S Renolleau… - The …, 2008 - journals.sagepub.com
Neonatal encephalopathy is a major predictor of neurodevelopmental disability in term
infants and occurs in 1 to 6 of every 1000 live term births. Despite improvements in perinatal …

Could perinatal asphyxia induce a synaptopathy? New highlights from an experimental model

MI Herrera, M Otero-Losada, LD Udovin… - Neural …, 2017 - Wiley Online Library
Birth asphyxia also termed perinatal asphyxia is an obstetric complication that strongly
affects brain structure and function. Central nervous system is highly susceptible to oxidative …

Fetal asphyctic preconditioning protects against perinatal asphyxia-induced apoptosis and astrogliosis in neonatal brain

K EM Cox-Limpens, E Strackx… - CNS & Neurological …, 2015 - ingentaconnect.com
Hypoxic-ischemic preconditioning is an endogenous mechanism in which exposure to a
sublethal episode of hypoxia-ischemia protects against a subsequent more severe episode …

Therapeutic strategies for leukodystrophic disorders resulting from perinatal asphyxia: focus on myelinating oligodendrocytes

J Janowska, J Sypecka - Molecular Neurobiology, 2018 - Springer
Perinatal asphyxia results from the action of different risk factors like complications during
pregnancy, preterm delivery, or long and difficult labor. Nowadays, it is still the leading …

Impact of neonatal hypoxia‐ischaemia on oligodendrocyte survival, maturation and myelinating potential

M Ziemka‐Nalecz, J Janowska, L Strojek… - Journal of cellular …, 2018 - Wiley Online Library
Hypoxic‐ischaemic episodes experienced at the perinatal period commonly lead to a
development of neurological disabilities and cognitive impairments in neonates or later in …

[HTML][HTML] Hypoxia diminishes the protective function of white-matter astrocytes in the developing brain

K Agematsu, L Korotcova, PD Morton, V Gallo… - The Journal of thoracic …, 2016 - Elsevier
Objectives White-matter injury after surgery is common in neonates with cerebral immaturity
secondary to in utero hypoxia. Astrocytes play a central role in brain protection; however, the …

Synaptoprotection in perinatal asphyxia: an experimental approach

MI Herrera, T Kobiec, R Kölliker-Frers… - Frontiers in Synaptic …, 2020 - frontiersin.org
Perinatal asphyxia (PA) is an obstetric complication occurring when the oxygen supply to the
newborn is temporally interrupted. This health problem is associated with high …

Astrocytic demise in the developing rat and human brain after hypoxic-ischemic damage

A Gelot, S Villapol, T Billette de Villemeur… - Developmental …, 2009 - karger.com
In order to approach the physiopathological mechanism underlying the selective
susceptibility of the immature brain to hypoxia-ischemia (HI), we have compared the lesions …