Safety and immunogenicity of a respiratory syncytial virus prefusion F (RSVPreF3) candidate vaccine in older adults: phase 1/2 randomized clinical trial
I Leroux-Roels, MG Davis, K Steenackers… - The Journal of …, 2023 - academic.oup.com
Background The aim of this study was to investigate safety and immunogenicity of vaccine
formulations against respiratory syncytial virus (RSV) containing the stabilized prefusion …
formulations against respiratory syncytial virus (RSV) containing the stabilized prefusion …
[HTML][HTML] Respiratory syncytial virus prefusion F protein vaccine in older adults
A Papi, MG Ison, JM Langley, DG Lee… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults …
infection, lower respiratory tract disease, clinical complications, and death in older adults …
Efficacy and safety of Respiratory Syncytial Virus (RSV) prefusion F protein vaccine (RSVPreF3 OA) in older adults over 2 RSV seasons
Background The adjuvanted RSV prefusion F protein–based vaccine (RSVPreF3 OA) was
efficacious against RSV-related lower respiratory tract disease (RSV-LRTD) in≥ 60-years …
efficacious against RSV-related lower respiratory tract disease (RSV-LRTD) in≥ 60-years …
A phase 1/2 study of a respiratory syncytial virus prefusion F vaccine with and without adjuvant in healthy older adults
Background Respiratory syncytial virus (RSV) is an important cause of disease in older
adults. We evaluated the safety and immunogenicity of a stabilized RSV prefusion F subunit …
adults. We evaluated the safety and immunogenicity of a stabilized RSV prefusion F subunit …
[HTML][HTML] Respiratory syncytial virus prefusion F protein vaccine is efficacious in older adults with underlying medical conditions
RG Feldman, R Antonelli-Incalzi… - Clinical Infectious …, 2024 - academic.oup.com
Background Older adults with chronic cardiorespiratory or endocrine/metabolic conditions
are at increased risk of respiratory syncytial virus (RSV)-related acute respiratory illness …
are at increased risk of respiratory syncytial virus (RSV)-related acute respiratory illness …
Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults
EE Walsh, G Pérez Marc, AM Zareba… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) infection causes considerable illness in older
adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based …
adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based …
Phase 1/2 randomized study of the immunogenicity, safety, and tolerability of a respiratory syncytial virus prefusion F vaccine in adults with concomitant inactivated …
AR Falsey, EE Walsh, DA Scott… - The Journal of …, 2022 - academic.oup.com
Background Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in
older adults and adults with comorbidities. An effective vaccine is needed. An investigational …
older adults and adults with comorbidities. An effective vaccine is needed. An investigational …
A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger …
AO Aliprantis, CA Shaw, P Griffin… - Human vaccines & …, 2021 - Taylor & Francis
ABSTRACT Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that
can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants …
can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants …
Vaccine efficacy in adults in a respiratory syncytial virus challenge study
B Schmoele-Thoma, AM Zareba, Q Jiang… - … England Journal of …, 2022 - Mass Medical Soc
Background Although human respiratory syncytial virus (RSV) is an important cause of
illness and death in older adults, no RSV vaccine has been licensed. Methods In a phase 2a …
illness and death in older adults, no RSV vaccine has been licensed. Methods In a phase 2a …
Phase 1 safety and immunogenicity study of a respiratory syncytial virus vaccine with an adenovirus 26 vector encoding prefusion F (Ad26. RSV. preF) in adults aged …
K Williams, AR Bastian, RA Feldman… - The Journal of …, 2020 - academic.oup.com
Background Despite the high disease burden of respiratory syncytial virus (RSV) in older
adults, there is no approved vaccine. We evaluated the experimental RSV vaccine, Ad26 …
adults, there is no approved vaccine. We evaluated the experimental RSV vaccine, Ad26 …
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