Absolute risk of oropharyngeal cancer after an HPV16-E6 serology test and potential implications for screening: results from the human papillomavirus cancer cohort …

HA Robbins, A Ferreiro-Iglesias… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early
detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or …

Kinetics of the human papillomavirus type 16 E6 antibody response prior to oropharyngeal cancer

AR Kreimer, M Johansson, EL Yanik… - JNCI: Journal of the …, 2017 - academic.oup.com
Abstract Background: In a European cohort, it was previously reported that 35% of
oropharyngeal cancer (OPC) patients were human papillomavirus type-16 (HPV16) …

[HTML][HTML] Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology–A proof-of …

CJ Busch, AS Hoffmann, D Viarisio, BT Becker… - …, 2022 - thelancet.com
Background The lack of detectable precancerous lesions poses challenges to the early
detection of human papillomavirus-driven oropharyngeal cancer (HPV-OPC). Antibodies …

Human papillomavirus 16 E6 antibodies in individuals without diagnosed cancer: a pooled analysis

KA Lang Kuhs, D Anantharaman, T Waterboer… - … Biomarkers & Prevention, 2015 - AACR
Background: The increasing incidence of oropharyngeal cancer in many developed
countries has been attributed to human papillomavirus type 16 (HPV16) infections. Recently …

Characterization of human papillomavirus antibodies in individuals with head and neck cancer

KAL Kuhs, M Pawlita, SP Gibson, NC Schmitt… - Cancer …, 2016 - Elsevier
Background Human papillomavirus type 16 (HPV16) E6 antibodies are a promising
biomarker of oropharyngeal cancer (OPC); however, seropositivity among non-OPC cases is …

[HTML][HTML] Timing of HPV16-E6 antibody seroconversion before OPSCC: findings from the HPVC3 consortium

AR Kreimer, A Ferreiro-Iglesias, M Nygard, N Bender… - Annals of …, 2019 - Elsevier
Background Human papillomavirus type 16 (HPV16)-E6 antibodies are detectable in
peripheral blood before diagnosis in the majority of HPV16-driven oropharyngeal squamous …

Evaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer

AR Kreimer, M Johansson, T Waterboer… - Journal of clinical …, 2013 - ascopubs.org
Purpose Human papillomavirus type 16 (HPV16) infection is causing an increasing number
of oropharyngeal cancers in the United States and Europe. The aim of our study was to …

Prevalence of oral and blood oncogenic human papillomavirus biomarkers among an enriched screening population: Baseline results of the MOUTH study

G D'Souza, SR Tewari, T Troy, T Waterboer, L Struijk… - Cancer, 2023 - Wiley Online Library
Background Human papillomavirus (HPV)‐related oropharyngeal cancer screening is being
explored in research studies, but strategies to identify an appropriate population are not …

Considerations in human papillomavirus–associated oropharyngeal cancer screening: a review

AT Day, C Fakhry, JA Tiro, KR Dahlstrom… - … –Head & Neck …, 2020 - jamanetwork.com
Importance The incidence of human papillomavirus (HPV)–positive oropharyngeal cancer
(OPC) is anticipated to rise over the next few decades until the effects of prophylactic …

Human papillomavirus 16 E 6 antibodies are sensitive for human papillomavirus–driven oropharyngeal cancer and are associated with recurrence

KA Lang Kuhs, AR Kreimer, S Trivedi, D Holzinger… - Cancer, 2017 - Wiley Online Library
BACKGROUND Human papillomavirus 16 (HPV16) E6 antibodies may be an early marker
of the diagnosis and recurrence of human papillomavirus–driven oropharyngeal cancer …