Packaging of drug molecules within microparticles and nanoparticles has become an
important strategy in intravascular drug delivery, where the particles are designed to protect …

In cancer therapy and imaging, the systemic passive delivery of particulate systems has
relied on the enhanced permeability and retention (EPR) effect: sufficiently small particles …

Intravascular drug delivery technologies majorly utilize spherical nanoparticles as carrier
vehicles. Their targets are often at the blood vessel wall or in the tissue beyond the wall …

Modification of nano/micro-particle physical parameters (eg size, shape, surface charge) has
proven to be an effective method to enhance their delivery abilities. Recently, advances in …

Targeting of drug carriers to the vascular wall is of interest for localized delivery of
therapeutics in many human diseases. Nanometer-sized spherical particles are widely …

Encapsulation of drugs in nano-and microparticles has been known as a promising
approach for efficient drug delivery. It has been well established that adjusting the …

The importance of the size of targeted, spherical drug carriers has been previously explored
and reviewed. Particle shape has emerged as an equally important parameter in …

Atherosclerotic plaques and thrombosis are chronic inflammatory complications and the
main manifestations of cardiovascular diseases (CVD), the leading cause of death globally …

Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …

A significant challenge that most therapeutic agents face is their inability to be delivered
effectively. Nanotechnology offers a solution to allow for safe, high-dose, specific delivery of …