Discrete roles for Rad54 and Rdh54 during homologous recombination

JB Crickard - Current Opinion in Genetics & Development, 2021 - Elsevier
Rad54 and Rdh54 are Snf2 DNA motor proteins that function during maintenance of
genomic integrity. Though highly related, Rad54 and Rdh54 have different biochemical and …

Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes

M Keymakh, J Dau, J Hu, B Ferlez, M Lisby… - PLoS …, 2022 - journals.plos.org
Homologous recombination (HR) is a double-strand break DNA repair pathway that
preserves chromosome structure. To repair damaged DNA, HR uses an intact donor DNA …

Rad54: the Swiss Army knife of homologous recombination?

WD Heyer, X Li, M Rolfsmeier… - Nucleic acids research, 2006 - academic.oup.com
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of
genetic information between homologous or near homologous (homeologous) DNA …

Functions of the Snf2/Swi2 family Rad54 motor protein in homologous recombination

SJ Ceballos, WD Heyer - Biochimica et Biophysica Acta (BBA)-Gene …, 2011 - Elsevier
Homologous recombination is a central pathway to maintain genomic stability and is
involved in the repair of DNA damage and replication fork support, as well as accurate …

Rad54, the motor of homologous recombination

AV Mazin, OM Mazina, DV Bugreev, MJ Rossi - DNA repair, 2010 - Elsevier
Homologous recombination (HR) performs crucial functions including DNA repair,
segregation of homologous chromosomes, propagation of genetic diversity, and …

Some disassembly required: role of DNA translocases in the disruption of recombination intermediates and dead-end complexes

LS Symington, WD Heyer - Genes & development, 2006 - genesdev.cshlp.org
Homologous recombination (HR) plays essential roles in the maintenance of genome
integrity in prokaryotic and eukaryotic organisms. The primary function of HR in mitotic cells …

Characterization of the interaction between the Saccharomyces cerevisiae Rad51 recombinase and the DNA translocase Rdh54

SR Santa Maria, YH Kwon, P Sung, HL Klein - Journal of Biological …, 2013 - ASBMB
The Saccharomyces cerevisiae Rdh54 protein is a member of the Swi2/Snf2 family of DNA
translocases required for meiotic and mitotic recombination and DNA repair. Rdh54 interacts …

Rad53 regulates the lifetime of Rdh54 at homologous recombination intermediates

J Hu, B Ferlez, J Dau, JB Crickard - Nucleic Acids Research, 2023 - academic.oup.com
Rdh54 is a conserved DNA translocase that participates in homologous recombination (HR),
DNA checkpoint adaptation, and chromosome segregation. Saccharomyces cerevisiae …

RAD54L regulates replication fork progression and nascent strand degradation in BRCA1/2-deficient cells.

ME Uhrig, N Sharma, P Maxwell… - Biorxiv: the Preprint …, 2023 - europepmc.org
RAD54L is a DNA motor protein with critical roles in homologous recombination DNA repair
(HR). In vitro, RAD54L was also shown to catalyze the reversal and restoration of model …

[HTML][HTML] RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis

MH Sanchez-Rebato, AM Bouatta, ME Gallego… - PLoS …, 2021 - journals.plos.org
An essential component of the homologous recombination machinery in eukaryotes, the
RAD54 protein is a member of the SWI2/SNF2 family of helicases with dsDNA-dependent …