Cisplatin (CDDP) has been identified as the primary chemotherapeutic agent for the
treatment of cervical cancer, but dose limiting toxicity is a key issue associated with its …

Significant heterogeneity in the tumor microenvironment of human cervical cancer patients is
known to challenge treatment outcomes in this population. The current standard of care for …

Purpose To evaluate pharmacokinetic profile, biodistribution and therapeutic effect of
cationic thermosensitive liposomes (CTSL) encapsulating doxorubicin (Dox) upon mild …

The antitumor effect of cisplatin-(CDDP)-encapsulated thermosensitive large unilamellar
liposome (ThLip) administration with hyperthermia (HT) was examined in mice bearing Meth …

This study reports on the activity of thermosensitive liposomes (TSLs) incorporating different
HSPC ratios in DPPC/MSPC/PEG2000-DSPE matrix (90/10/4) plus mild hyperthermia …

Thermoresponsive drug delivery systems have been used previously to deliver
chemotherapeutic agents to tumors in a hyperthermic microenvironment. The objective of …

Objectives: In this study, we combined chemo-and hyperthermia therapy in a low
temperature-sensitive liposome (LTSL) for potential cancer treatment. Methods: Docetaxel …

Systemic chemotherapy of solid tumors could be enhanced by local hyperthermia (HT) in
combination with thermosensitive liposomes (TSL) as drug carriers. In such an approach …

Non-invasive in vivo imaging of drug distribution enables real-time monitoring and
prediction of therapeutic responses to treatment. We have developed a thermosensitive …

Objective Cisplatin-based chemotherapy has been shown to improve survival in cervical
cancer; however, treatment is associated with tumor resistance and significant toxicity …