Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula

MV Tsapenko, LV d'Uscio, JP Grande… - American Journal …, 2012 - journals.physiology.org
Vascular access dysfunction causes morbidity in hemodialysis patients. This study
examined the generation and pathobiological significance of superoxide anion in a rat …

Functioning of an arteriovenous fistula requires heme oxygenase-2

L Kang, JP Grande, G Farrugia… - American Journal …, 2013 - journals.physiology.org
Heme oxygenase-2 (HO-2), the constitutive isoform of the heme-degrading enzyme heme
oxygenase, may serve as an anti-inflammatory vasorelaxant, in part, by generating carbon …

A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1

L Kang, JP Grande, ML Hillestad… - American Journal …, 2016 - journals.physiology.org
The arteriovenous fistula (AVF) is the preferred hemodialysis vascular access, but it is
complicated by high failure rates and attendant morbidity. This study provides the first …

[HTML][HTML] Characterization of a model of an arteriovenous fistula in the rat: the effect of L-NAME

AJ Croatt, JP Grande, MC Hernandez… - The American journal of …, 2010 - Elsevier
Vascular access dysfunction contributes to the mortality of patients undergoing chronic
hemodialysis. The present study analyzed the changes that evolve in a femoral …

[PDF][PDF] SUPEROXIDE DISMUTASE ACTIVITY AND EXPRESSION IN HUMAN

TJ Guzik, R Olszanecki, J Sadowski… - Journal of Physiology …, 2005 - academia.edu
Venous bypass grafts are more prone to accelerated atherosclerosis than arterial grafts,
which is partly related to increased oxidative stress and diminished nitric oxide …

Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula

L Kang, S Yamada, MC Hernandez… - American Journal …, 2011 - journals.physiology.org
The study of hemodynamic alterations following the creation of an arteriovenous fistula
(AVF) is relevant to vascular adaptive responses and hemodialysis access dysfunction. This …

Enhanced superoxide production in experimental venous bypass graft intimal hyperplasia: role of NAD (P) H oxidase

NEJ West, TJ Guzik, E Black… - … thrombosis, and vascular …, 2001 - Am Heart Assoc
Vein graft intimal hyperplasia, due to smooth muscle cell (SMC) proliferation, remains a
limiting factor in long-term vein graft patency. Increased superoxide production regulates …

[HTML][HTML] Mechanisms of increased vascular superoxide production in human varicose veins

B Guzik, M Chwala, P Matusik, D Ludew… - Polskie Archiwum …, 2011 - ncbi.nlm.nih.gov
Varicose veins is one of the most common diseases observed in developed countries.
Recent studies have shown that oxidative stress is increased in varicose veins, particularly …

Angiotensin II–NAD (P) H oxidase–stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla

T Mori, AW Cowley Jr - Hypertension, 2003 - Am Heart Assoc
The source of superoxide (O2·−) production and cell-to-cell interactions of O2·− and nitric
oxide (NO) in response to angiotensin II (AngII) were studied by fluorescence microscopic …

[PDF][PDF] Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction?

G Zalba, FJ Beaumont, G San José… - Nephrology Dialysis …, 2001 - researchgate.net
Background. Increases in oxidant stress, ie excessive production of superoxide anion PO2
Ā), have been reported in different models of hypertension. This study was designed to test …