Immunomodulatory activity of fucoidan against aspirin-induced gastric mucosal damage in rats

HRB Raghavendran, P Srinivasan, S Rekha - International …, 2011 - Elsevier
Gastric ulcers and related complications associated with the use of non-steroidal anti-
inflammatory drugs (NSAIDs), such as aspirin, represent a major global health problem. In …

Effect of fucoidan on aspirin-induced stomach ulceration in rats

J Choi, HRB Raghavendran, NY Sung, JH Kim… - Chemico-Biological …, 2010 - Elsevier
In this study, the effects of fucoidan on aspirin-induced ulcers in rats were evaluated: both
biochemical and immunological parameters were taken into consideration. The status of …

Anti-ulcerogenic effect of cavidine against ethanol-induced acute gastric ulcer in mice and possible underlying mechanism

W Li, X Wang, H Zhang, Z He, W Zhi, F Liu… - International …, 2016 - Elsevier
Cavidine, a major alkaloid compound isolated from Corydalis impatiens, has various
pharmacological effects but its effect on gastric ulcer has not been previously explored. The …

Fucoidan mitigates gastric ulcer injury through managing inflammation, oxidative stress, and NLRP3-mediated pyroptosis

HM Selim, WA Negm, MF Hawwal, IA Hussein… - International …, 2023 - Elsevier
This study aimed to elucidate the gastro-protective effect of fucoidan against ethanol-
induced gastric ulcer mediated via NLRP3-induced pyroptosis as an underlying mechanism …

Curative effects of fucoidan on acetic acid induced ulcerative colitis in rats via modulating aryl hydrocarbon receptor and phosphodiesterase-4

A Bagalagel, R Diri, A Noor, D Almasri… - … Medicine and Therapies, 2022 - Springer
Background Ulcerative colitis (UC) is an inflammatory bowel disease. Fucoidan, sulfated
polysaccharide of brown seaweed, demonstrates various pharmacological actions as anti …

Protective effect of fustin against ethanol-activated gastric ulcer via downregulation of biochemical parameters in rats

SJ Gilani, MN Bin-Jumah, FA Al-Abbasi… - ACS …, 2022 - ACS Publications
The fustin plant-derived bioflavonoid obtained from a common plant known as lacquer tree
from family Anacardiaceae, formally known as Rhus verniciflua Stokes, is known to exert a …

[HTML][HTML] Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation

YI Mahmoud, EA Abd El-Ghffar - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Aspirin is a commonly prescribed non steroidal anti-inflammatory drug, but its prolonged use
injures the gastric mucosa. The present study was carried out to evaluate the ameliorative …

Fucoidan prevents concanavalin A-induced liver injury through induction of endogenous IL-10 in mice

A Saito, M Yoneda, S Yokohama, M Okada… - Hepatology …, 2006 - Elsevier
Fucoidan is a complex of sulfated polysaccharides derived from non-mammalian origin such
as marine brown algae and induces cytokine expression. We investigated the effect of …

Protective role of ascorbic acid isolated from Cissus quadrangularis on NSAID induced toxicity through immunomodulating response and growth factors expression

M Jainu, KV Mohan - International immunopharmacology, 2008 - Elsevier
The present study investigate the effect of ascorbic acid, the major bioactive component
isolated from Cissus quadrangularis extract (CAA) on inflammatory cytokines and growth …

Gastroprotective effects of sulforaphane and thymoquinone against acetylsalicylic acid–induced gastric ulcer in rats

S Zeren, Z Bayhan, FE Kocak, C Kocak… - journal of surgical …, 2016 - Elsevier
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) commonly cause gastric ulcers
(GUs). We investigated the effects of sulforaphane (SF) and thymoquinone (TQ) in rats with …