More codeine fatalities after tonsillectomy in North American children

LE Kelly, M Rieder, J van den Anker, B Malkin… - …, 2012 - publications.aap.org
In 2009 we reported the fatal case of a toddler who had received codeine after
adenotonsillectomy for obstructive sleep apnea syndrome. The child was an ultra-rapid …

Apnea in a child after oral codeine: a genetic variant–an ultra‐rapid metabolizer

P Voronov, HJ Przybylo, N Jagannathan - Pediatric Anesthesia, 2007 - Wiley Online Library
We present a case of a 29 months old previously healthy child who experienced apnea
resulting in brain injury following a dose of acetaminophen and codeine 2 days after an …

A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol.

G Orliaguet, J Hamza, V Couloigner, F Denoyelle… - Pediatrics, 2015 - europepmc.org
A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol.
- Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

[HTML][HTML] New evidence about an old drug—risk with codeine after adenotonsillectomy

JA Racoosin, DW Roberson… - … England Journal of …, 2013 - Mass Medical Soc
New Evidence about an Old Drug — Risk with Codeine after Adenotonsillectomy | NEJM Skip
to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare …

Opioid-induced respiratory depression in paediatrics: a review of case reports

M Niesters, F Overdyk, T Smith, L Aarts… - British journal of …, 2013 - academic.oup.com
Opioids remain the cornerstone of modern-day pain treatment, also in the paediatric
population. Opioid treatment is potentially life-threatening, although there are no numbers …

Codeine: time to say “no”

JD Tobias, TP Green, CJ Coté, R Agarwal… - …, 2016 - publications.aap.org
Background Codeine (3-methylmorphine) is a naturally occurring methylated morphine that
has seen widespread clinical use for> 50 years as an analgesic and an antitussive agent …

An anesthetic management protocol to decrease respiratory complications after adenotonsillectomy in children with severe sleep apnea

S Raghavendran, H Bagry, G Detheux… - Anesthesia & …, 2010 - journals.lww.com
BACKGROUND: A high incidence of respiratory morbidity after adenotonsillectomy is
reported in children with obstructive sleep apnea syndrome (OSAS). In an effort to decrease …

Fatal hydrocodone overdose in a child: pharmacogenetics and drug interactions

P Madadi, D Hildebrandt, IY Gong, UI Schwarz… - …, 2010 - publications.aap.org
Fatal opioid toxicity occurred in a developmentally delayed child aged 5 years 9 months who
was inadvertently administered high doses of hydrocodone for a respiratory tract infection …

Morphine or ibuprofen for post-tonsillectomy analgesia: a randomized trial

LE Kelly, DD Sommer, J Ramakrishna, S Hoffbauer… - …, 2015 - publications.aap.org
BACKGROUND: Pediatric sleep disordered breathing is often caused by hypertrophy of the
tonsils and is commonly managed by tonsillectomy. There is controversy regarding which …

Death or neurologic injury after tonsillectomy in children with a focus on obstructive sleep apnea: Houston, we have a problem!

CJ Coté, KL Posner, KB Domino - Anesthesia & Analgesia, 2014 - journals.lww.com
BACKGROUND: Obesity is epidemic in the United States and with it comes an increased
incidence of obstructive sleep apnea (OSA). Evidence regarding opioid sensitivity as well as …