An update of current cannabis-based pharmaceuticals in pain medicine

I Urits, M Borchart, M Hasegawa, J Kochanski… - Pain and Therapy, 2019 - Springer
Cannabis users have long reported therapeutic properties of the plant for a variety of
conditions, some of which include nausea, emesis, seizures, cancer, neurogenic diseases …

Cannabis for chronic pain: challenges and considerations

EA Romero‐Sandoval, JE Fincham… - … : The Journal of …, 2018 - Wiley Online Library
The National Academies of Sciences, Engineering, and Medicine has found substantial
evidence that cannabis (plant) is effective for the treatment of chronic pain in adults, and …

Cannabinoids in the management of difficult to treat pain

EB Russo - Therapeutics and clinical risk management, 2008 - Taylor & Francis
This article reviews recent research on cannabinoid analgesia via the endocannabinoid
system and non-receptor mechanisms, as well as randomized clinical trials employing …

Cannabinoid formulations and delivery systems: Current and future options to treat pain

B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …

Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes

J Manzanares, MD Julian… - Current …, 2006 - ingentaconnect.com
Cannabis extracts and synthetic cannabinoids are still widely considered illegal substances.
Preclinical and clinical studies have suggested that they may result useful to treat diverse …

A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in the management of chronic pain

MA Überall - Journal of pain research, 2020 - Taylor & Francis
The 20% prevalence of chronic pain in the general population is a major health concern
given the often profound associated impairment of daily activities, employment status, and …

Cannabinoid analgesia as a potential new therapeutic option in the treatment of chronic pain

TL Burns, JR Ineck - Annals of Pharmacotherapy, 2006 - journals.sagepub.com
Objective: To review the literature concerning the physiology of the endocannabinoid
system, current drug development of cannabinoid agonists, and current clinical research on …

[HTML][HTML] The analgesic potential of cannabinoids

J Elikottil, P Gupta, K Gupta - Journal of opioid management, 2009 - ncbi.nlm.nih.gov
Historically and anecdotally cannabinoids have been used as analgesic agents. In recent
years, there has been an escalating interest in developing cannabis-derived medications to …

[HTML][HTML] Cannabinoids and pain: new insights from old molecules

S Vučković, D Srebro, KS Vujović, Č Vučetić… - Frontiers in …, 2018 - frontiersin.org
Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …