Several gene mutations have been identified in Hirschsprung's disease, a condition
characterized by distal gut aganglionosis. The mechanisms by which these genetic defects …

The enteric nervous system (ENS) is a rich network of neurons and glial cells that comprise
the gastrointestinal tract's intrinsic nervous system and are responsible for controlling …

Genes associated with Hirschsprung disease, a failure to form enteric ganglia in the hindgut,
were highly up-regulated in gut neural crest stem cells relative to whole-fetus RNA. One of …

Hirschsprung disease (HD), or congenital aganglionosis coli, is a birth defect with
heterogeneous causes. In an effort to understand the molecular and cellular bases for this …

The enteric nervous system is the part of the autonomic nervous system that directly controls
the gastrointestinal tract. Derived from a multipotent, migratory cell population called the …

Aim: To isolate and characterise Enteric Nervous System (ENS) stem cells from the gut of
post-natal miRet 51/51 “Hirschsprung's mouse”. Methods: Cultures of dissociated myenteric …

The work of this thesis investigates the development of, and treatment options for,
Hirschsprung disease (HSCR). We explore the missing heritability that is seen in HSCR …

1 日目 Heather M. Young Department of Anatomy & Cell Biology, University of Melbourne,
Australia 第 1 会場 コンコード ボールルーム A 5 月 31 日 8: 20~ 10: 00 シンボジウム 1 …

Hirschsprung's disease (HSCR) is defined by an absence of enteric neurons of the distal
part of the gastrointestinal tract. HSCR results from a failure of the enteric neural crest …

Hirschsprung's disease affects 1 in 5000 newborns and is caused by an absence of
ganglion cells in a variable length of the distal gut. It commonly presents in the newborn …