Endogenous mediators regulating acute inflammatory responses in both the induction and
resolution phases of inflammatory processes are pivotal in host defense and tissue …

Semaphorins play an essential role in axonal guidance, and emerging evidence points to
diverse functions of several Semaphorin family members in the immune system …

Recent studies identified basic biological principles that are shared by the immune and the
nervous system. One of these analogies applies to the orchestration of cellular migration …

Abstract Semaphorin 3E (Sema3E) is a secreted protein that was initially discovered as a
neuronal guidance cue. Recent evidence showed that Sema3E plays an essential role in …

Objective—The persistence of myeloid-derived cells in the artery wall is a characteristic of
advanced atherosclerotic plaques. However, the mechanisms by which these cells are …

The global prevalence of metabolic diseases, such as obesity, diabetes, and
atherosclerosis, is rapidly increasing and has now reached epidemic proportions. Chronic …

Striking parallels exist between immune and nervous system cellular signalling
mechanisms. Molecules originally shown to be critical for immune responses also serve …

Semaphorins have been classically defined as axonal signalling cues involved in central
nervous system (CNS) development, but in adults these molecules are expressed in distinct …

Long-term inflammatory processes directed at a particular endogenous or exogenous
antigen, or sometimes of unknown etiology, form the pathogenetic basis for many …

Semaphorins are axon guidance factors that assist growing axons in finding appropriate
targets and forming synapses. Emerging evidence suggests that semaphorins are involved …