Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer
Human papillomavirus (HPV) testing has been recently introduced as an alternative to
cytology for cervical cancer screening. However, since most HPV infections clear without …
cytology for cervical cancer screening. However, since most HPV infections clear without …
Human papillomavirus DNA methylation as a biomarker for cervical precancer: consistency across 12 genotypes and potential impact on management of HPV-positive …
Abstract Purpose: Human papillomavirus (HPV) DNA methylation testing is a promising
triage option for women testing HPV positive during cervical cancer screening. However, the …
triage option for women testing HPV positive during cervical cancer screening. However, the …
A four‐gene methylation marker panel as triage test in high‐risk human papillomavirus positive patients
JJH Eijsink, A Lendvai, V Deregowski… - … journal of cancer, 2012 - Wiley Online Library
Cervical neoplasia‐specific biomarkers, eg DNA methylation markers, with high sensitivity
and specificity are urgently needed to improve current population‐based screening on (pre) …
and specificity are urgently needed to improve current population‐based screening on (pre) …
DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort
RW van Leeuwen, A Oštrbenk, M Poljak… - … Journal of Cancer, 2019 - Wiley Online Library
Objective triage strategies are required to prevent unnecessary referrals for colposcopy in
population‐based screening programs using primary high‐risk human papillomavirus …
population‐based screening programs using primary high‐risk human papillomavirus …
Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade
D Bryant, A Tristram, T Liloglou, S Hibbitts… - Journal of Clinical …, 2014 - Elsevier
Abstract Background Persistent infection with Human Papillomavirus (HPV) type 16 causes
the majority of cervical cancers. Genital HPV infection is very common, but neoplastic …
the majority of cervical cancers. Genital HPV infection is very common, but neoplastic …
[HTML][HTML] DNA methylation as a triage tool for cervical cancer screening–A meeting report
FR Burdier, B Nedjai, RDM Steenbergen… - Preventive medicine …, 2024 - Elsevier
Introduction DNA methylation is proposed as a novel biomarker able to monitor molecular
events in human papillomavirus (HPV) infection pathophysiology, enabling the distinction …
events in human papillomavirus (HPV) infection pathophysiology, enabling the distinction …
A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes
AR Brentnall, N Vasiljević… - … journal of cancer, 2014 - Wiley Online Library
Testing for high‐risk (hr) types of human papillomavirus (HPV) is highly sensitive as a
screening test of high‐grade cervical intraepithelial neoplastic (CIN2/3) disease, the …
screening test of high‐grade cervical intraepithelial neoplastic (CIN2/3) disease, the …
A promising DNA methylation signature for the triage of high-risk human papillomavirus DNA-positive women
A Hansel, D Steinbach, C Greinke, M Schmitz, J Eiselt… - PloS one, 2014 - journals.plos.org
High-risk human papillomavirus (hrHPV)-DNA testing is frequently performed parallel to
cytology for the detection of high-grade dysplasia and cervical cancer particularly in women …
cytology for the detection of high-grade dysplasia and cervical cancer particularly in women …
[HTML][HTML] Credentialing of DNA methylation assays for human genes as diagnostic biomarkers of cervical intraepithelial neoplasia in high-risk HPV positive women
N Vasiljević, D Scibior-Bentkowska, AR Brentnall… - Gynecologic …, 2014 - Elsevier
Objective Testing for high risk human papillomavirus (HR-HPV) is increasing; however due
to limitations in specificity there remains a need for better triage tests. Research efforts have …
to limitations in specificity there remains a need for better triage tests. Research efforts have …
Human papillomavirus DNA methylation as a potential biomarker for cervical cancer
Sexually transmitted carcinogenic human papillomavirus (HPV) infections are extraordinarily
prevalent worldwide. However, most incident HPV infections clear within a few years …
prevalent worldwide. However, most incident HPV infections clear within a few years …