Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Nature genetics, 2010 - nature.com
Consistent but indirect evidence has implicated genetic factors in smoking behavior,. We
report meta-analyses of several smoking phenotypes within cohorts of the Tobacco and …

Genome-wide meta-analyses of smoking behaviors in African Americans

SP David, A Hamidovic, GK Chen, AW Bergen… - Translational …, 2012 - nature.com
The identification and exploration of genetic loci that influence smoking behaviors have
been conducted primarily in populations of the European ancestry. Here we report results of …

Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

K Xu, B Li, KA McGinnis, R Vickers-Smith, C Dao… - Nature …, 2020 - nature.com
Here we report a large genome-wide association study (GWAS) for longitudinal smoking
phenotypes in 286,118 individuals from the Million Veteran Program (MVP) where we …

Sequence variants at CHRNB3CHRNA6 and CYP2A6 affect smoking behavior

TE Thorgeirsson, DF Gudbjartsson, I Surakka… - Nature …, 2010 - nature.com
Smoking is a common risk factor for many diseases. We conducted genome-wide
association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers …

A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population

MD Li, JZ Ma, R Cheng, RT Dupont, NJ Williams… - BMC genetics, 2003 - Springer
Background Although many years of genetic epidemiological studies have demonstrated
that genetics plays a significant role in determining smoking behavior, little information is …

The genetics of tobacco use: methods, findings and policy implications

W Hall, P Madden, M Lynskey - Tobacco control, 2002 - tobaccocontrol.bmj.com
Research on the genetics of smoking has increased our understanding of nicotine
dependence, and it is likely to illuminate the mechanisms by which cigarette smoking …

The genetic basis for smoking behavior: a systematic review and meta-analysis

MR Munafo, TG Clark, EC Johnstone… - Nicotine & Tobacco …, 2004 - academic.oup.com
Considerable evidence indicates that smoking behavior is under a degree of genetic
influence. We conducted a systematic review of candidate gene studies of smoking behavior …

Genome-wide and candidate gene association study of cigarette smoking behaviors

N Caporaso, F Gu, N Chatterjee, J Sheng-Chih, K Yu… - PloS one, 2009 - journals.plos.org
The contribution of common genetic variation to one or more established smoking behaviors
was investigated in a joint analysis of two genome wide association studies (GWAS) …

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

AM Erzurumluoglu, M Liu, VE Jackson, DR Barnes… - Molecular …, 2020 - nature.com
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer,
common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have …

Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs

GR Uhl, QR Liu, T Drgon, C Johnson, D Walther… - BMC genetics, 2007 - Springer
Background Classical genetic studies indicate that nicotine dependence is a substantially
heritable complex disorder. Genetic vulnerabilities to nicotine dependence largely overlap …