[HTML][HTML] Evidence of inbreeding depression on human height
R McQuillan, N Eklund, N Pirastu, M Kuningas… - PLoS …, 2012 - journals.plos.org
Stature is a classical and highly heritable complex trait, with 80%–90% of variation
explained by genetic factors. In recent years, genome-wide association studies (GWAS) …
explained by genetic factors. In recent years, genome-wide association studies (GWAS) …
Signals of polygenic adaptation on height have been overestimated due to uncorrected population structure in genome-wide association studies
M Sohail, RM Maier, A Ganna, A Bloemendal… - BioRxiv, 2018 - biorxiv.org
Genetic predictions of height differ significantly among human populations and these
differences are too large to be explained by random genetic drift. This observation has been …
differences are too large to be explained by random genetic drift. This observation has been …
From Galton to GWAS: quantitative genetics of human height
PM Visscher, B McEvoy, J Yang - Genetics research, 2010 - cambridge.org
Height has been studied in human genetics since the late 1800s. We review what we have
learned about the genetic architecture of this trait from the resemblance between relatives …
learned about the genetic architecture of this trait from the resemblance between relatives …
[HTML][HTML] The genetic correlation between height and IQ: shared genes or assortative mating?
MC Keller, CE Garver-Apgar, MJ Wright… - PLoS …, 2013 - journals.plos.org
Traits that are attractive to the opposite sex are often positively correlated when scaled such
that scores increase with attractiveness, and this correlation typically has a genetic …
that scores increase with attractiveness, and this correlation typically has a genetic …
A commentary on 'common SNPs explain a large proportion of the heritability for human height'by Yang et al.(2010)
Recently a paper authored by ourselves and a number of co-authors about the proportion of
phenotypic variation in height that is explained by common SNPs was published in Nature …
phenotypic variation in height that is explained by common SNPs was published in Nature …
[HTML][HTML] Finding missing heritability in less significant Loci and allelic heterogeneity: genetic variation in human height
G Zhang, R Karns, G Sun, SR Indugula, H Cheng… - PloS one, 2012 - journals.plos.org
Genome-wide association studies (GWAS) have identified many common variants
associated with complex traits in human populations. Thus far, most reported variants have …
associated with complex traits in human populations. Thus far, most reported variants have …
[HTML][HTML] Genome-wide compound heterozygote analysis highlights alleles associated with adult height in Europeans
K Zhong, G Zhu, X Jing, AEJ Hendriks, SLS Drop… - Human genetics, 2017 - Springer
Adult height is the most widely genetically studied common trait in humans; however, the
trait variance explainable by currently known height-associated single nucleotide …
trait variance explainable by currently known height-associated single nucleotide …
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
M Sohail, RM Maier, A Ganna, A Bloemendal… - Elife, 2019 - elifesciences.org
Genetic predictions of height differ among human populations and these differences have
been interpreted as evidence of polygenic adaptation. These differences were first detected …
been interpreted as evidence of polygenic adaptation. These differences were first detected …
Reaching new heights: insights into the genetics of human stature
MN Weedon, TM Frayling - Trends in genetics, 2008 - cell.com
Human height is a highly heritable, classic polygenic trait. Until recently, there had been
limited success in identifying the specific genetic variants that explain normal variation of …
limited success in identifying the specific genetic variants that explain normal variation of …
Population genetic differentiation of height and body mass index across Europe
MR Robinson, G Hemani, C Medina-Gomez… - Nature …, 2015 - nature.com
Across-nation differences in the mean values for complex traits are common,,,,,,,, but the
reasons for these differences are unknown. Here we find that many independent loci …
reasons for these differences are unknown. Here we find that many independent loci …