Genome-wide association studies (GWAS) have identified more than 50,000 unique
associations with common human traits. While this represents a substantial step forward …

Background: Much effort has been expended on identifying the genetic determinants of
multiple sclerosis (MS). Existing large-scale genome-wide association study (GWAS) …

Multiple sclerosis (MS) is an inflammatory neurodegenerative disease with complex
aetiology. A haplotype within the major histocompatibility region is the major risk factor for …

Multiple sclerosis (MS) is an inflammatory CNS disease with a substantial genetic
component, originally mapped to only the human leukocyte antigen (HLA) region. In the last …

Genome-wide association studies (GWAS) testing several hundred thousand SNPs have
been performed in multiple sclerosis (MS) and other complex diseases. Typically, the …

Large‐scale genetic studies of multiple sclerosis have identified over 230 risk effects across
the human genome, making it a prototypical common disease with complex genetic …

The efforts of the Human Genome Project are beginning to provide important findings for
human health. Technological advances in the laboratory, particularly in characterizing …

Genome-wide association studies (GWAS) successfully identified multiple sclerosis (MS)
susceptibility variants. Despite this notable progress, understanding the biological context of …

Multiple sclerosis is a complex neurological disease, with∼ 20% of risk heritability
attributable to common genetic variants, including> 230 identified by genome-wide …

Multiple sclerosis (MS) is a common complex neurodegenerative disease of the central
nervous system. It develops with autoimmune inflammation and demyelination. Genome …